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Acinetobacter baumannii efflux pump inhibitor 1

Also Known As:

(E)-4-((4-chlorobenzylidene)amino)benezenesulfonamide; ABEPI1

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - Acinetobacter baumannii efflux pump inhibitor 1: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - Acinetobacter baumannii efflux pump inhibitor 1: 1

Experts

1.	Barnett, Pamela: 1 article (11/2014)
2.	Blanchard, Catlyn: 1 article (11/2014)
3.	Dunman, Paul M: 1 article (11/2014)
4.	Perlmutter, Jessamyn: 1 article (11/2014)

Related Diseases

1.

Gram-Negative Bacterial Infections

11/01/2014 - "While both compounds also inhibited the antibiotic efflux properties of the bacterial pathogen Pseudomonas aeruginosa, they did not display significant cytotoxicity toward human cells or mammalian Ca(2+) channel inhibitory effects, suggesting that ABEPI1 and ABEPI2 represent promising structural scaffolds for the development of new classes of bacterial antibiotic efflux pump inhibitors that can be used to potentiate the activities of current and future antibiotics for the therapeutic intervention of Gram-negative bacterial infections. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Acinetobacter baumannii efflux pump inhibitor 2