HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

N- (4- hydroxyphenethyl)- 3- mercapto- 2- methylpropanamide

a PPARgamma partial agonist with antidiabetic activity; structure in first source

Also Known As:

MDCCCL1636

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Li, Shan: 1 article (06/2015)
2.	Liang, Cai-li: 1 article (06/2015)
3.	Liu, Hui-juan: 1 article (06/2015)
4.	Liu, Yan-rong: 1 article (06/2015)
5.	Meng, Jing: 1 article (06/2015)
6.	Song, Fei: 1 article (06/2015)
7.	Sun, Tao: 1 article (06/2015)
8.	Wang, Jing: 1 article (06/2015)
9.	Xiao, Ting: 1 article (06/2015)
10.	Zhang, Bo: 1 article (06/2015)

Related Diseases

1.	Dyslipidemias (Dyslipidemia) 06/01/2015 - "High-fat diet-fed streptozotocin-induced diabetic rats treated with MDCCCL1636 for 56 days displayed reduced fasting serum glucose and reversed dyslipidemia and pancreatic damage without significant weight gain. "
2.	Weight Gain 06/01/2015 - "High-fat diet-fed streptozotocin-induced diabetic rats treated with MDCCCL1636 for 56 days displayed reduced fasting serum glucose and reversed dyslipidemia and pancreatic damage without significant weight gain. "
3.	Insulin Resistance 06/01/2015 - "MDCCCL1636 showed a potential antidiabetic effect on an insulin-resistance model of human hepatocarcinoma cells (HepG2). "
4.	Hepatocellular Carcinoma (Hepatoma) 06/01/2015 - "MDCCCL1636 also potentiated glucose consumption and inhibited the impairment in insulin signaling targets, such as AKT, glycogen synthase kinase 3β, and glycogen synthase, in HepG2 human hepatoma cells. "
5.	Type 2 Diabetes Mellitus (MODY) 06/01/2015 - "Overall, our results suggest that MDCCCL1636 is a promising candidate for the prevention and treatment of type 2 diabetes mellitus. "

Related Drugs and Biologics

1.	Glycogen Synthase Kinases
2.	Streptozocin (Streptozotocin)
3.	Insulin (Novolin)
4.	Hypoglycemic Agents (Hypoglycemics)
5.	Glycogen Synthase (Synthase I)
6.	Glucose (Dextrose)