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CAY10598

a prostaglandin EP4 receptor agonist; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Tetrazoles: 14
      - CAY10598: 2
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - CAY10598: 2

Experts

1.	Bayarmagnai, Battuya: 1 article (03/2017)
2.	Cambi, Alessandra: 1 article (03/2017)
3.	Gligorijevic, Bojana: 1 article (03/2017)
4.	Perrin, Louisiane: 1 article (03/2017)
5.	Tönisen, Felix: 1 article (03/2017)
6.	van den Dries, Koen: 1 article (03/2017)
7.	Chae, I G: 1 article (11/2014)
8.	Chun, K-S: 1 article (11/2014)
9.	Jeong, C-H: 1 article (11/2014)
10.	Kim, D-H: 1 article (11/2014)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 11/01/2014 - "The present study was aimed at investigating the effect of the EP4-specific agonist CAY10598 in human colon cancer HCT116 cells. " 11/01/2014 - "Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells."
2.	Breast Neoplasms (Breast Cancer) 03/01/2017 - "The results show that stimulation with the selective EP4 agonist CAY10598 or PGE2 promotes invadopodia-mediated degradation of the ECM, as well as the invasion of breast cancer cells in in vitro models. "

Related Drugs and Biologics

1.	Dinoprostone (PGE2)