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vincosamide

isolated from Anthocephalus cadamba; structure in first source

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - vincosamide: 6
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        vincosamide: 6
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        vincosamide: 6

Experts

1.	Ames, Franciele Q: 1 article (11/2021)
2.	Amorim, André M A: 1 article (11/2021)
3.	Bersani-Amado, Ciomar A: 1 article (11/2021)
4.	Corrêa, José G S: 1 article (11/2021)
5.	Peixoto, Matheus A: 1 article (11/2021)
6.	Pomini, Armando M: 1 article (11/2021)
7.	Ruiz, Ana Lúcia T G: 1 article (11/2021)
8.	Santin, Silvana M O: 1 article (11/2021)
9.	de Carvalho, João E: 1 article (11/2021)
10.	de Moura, Vagner M: 1 article (11/2021)

Related Diseases

1.	Cardiotoxicity 06/01/2017 - "Cardioprotective effect of N, α-L-rhamnopyranosyl vincosamide (VR), isolated from the leaves of Moringa oleifera plant in doxorubicin (Dox)-induced cardiac toxicity rats was evaluated. " 02/15/2013 - "Hitherto unknown protective effect of N,α-L-rhamnopyranosyl vincosamide (VR), isolated from Moringa oleifera leaves in isoproterenol (ISO)-induced cardiac toxicity was evaluated in rats. " 06/01/2017 - "Cardioprotective effect of magnetic hydrogel nanocomposite loaded N,α-L-rhamnopyranosyl vincosamide isolated from Moringa oleifera leaves against doxorubicin-induced cardiac toxicity in rats: in vitro and in vivo studies."
2.	Inflammation (Inflammations) 10/01/2019 - "Psychotria leiocarpa Extract and Vincosamide Reduce Chemically-Induced Inflammation in Mice and Inhibit the Acetylcholinesterase Activity." 01/01/2021 - "Studies show that the phytochemical compounds, for example, N,α-L-rhamnopyranosyl vincosamide and quercetin, have the molecular function of antioxidant, anti-inflammation, and anti-apoptosis. "
3.	Neoplasms (Cancer) 10/01/2022 - "Vincosamide (Vinco) was first identified in the methanolic extract of the leaves of Psychotria leiocarpa, and Vinco has important anti-inflammatory effects and activity against cholinesterase, Vinco also has a trait to anti-tumor. "
4.	Hepatocellular Carcinoma (Hepatoma) 10/01/2022 - "Vincosamide Has a Function for Inhibiting Malignant Behaviors of Hepatocellular Carcinoma Cells."
5.	Glioma (Gliomas) 11/01/2021 - "Methanolic extract, non-alkaloidal and alkaloidal fractions exhibited strong growth inhibition for ovarian cell lines (OVCAR-3, GI50 = 3.8 at 16.3 µg mL-1) and the vincosamide alkaloid revealed selective effect on the growth of glioma cell lines (U251, GI50 = 33.0 µg mL-1) compared with doxorubicin (DOX, GI50 = 0.42 and 0.025 µg mL-1, respectively) anticancer drug. "

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Phytochemicals
3.	Quercetin
4.	Antioxidants
5.	Nanogels
6.	Isoproterenol (Isoprenaline)
7.	Cholinesterases (Cholinesterase)
8.	Alkaloids
9.	Acetylcholinesterase
10.	isothiocyanic acid