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N- (3- (1- (2- nitrophenyl)- 1H- pyrrol- 2- yl)allylidenamino)guanidine

an agonist of both melanocortin receptors 1 and 2

Also Known As:

AP1189; N-(3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidenamino)guanidinium acetate

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amidines: 14
  - Guanidines: 29
    - N-(3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidenamino)guanidine: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - N-(3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidenamino)guanidine: 1

Experts

1.	Cooray, Sadani N: 1 article (04/2015)
2.	Gobbetti, Thomas: 1 article (04/2015)
3.	Jonassen, Thomas E N: 1 article (04/2015)
4.	Montero-Melendez, Trinidad: 1 article (04/2015)
5.	Perretti, Mauro: 1 article (04/2015)

Related Diseases

1.	Joint Diseases (Joint Disease) 04/01/2015 - "Finally, given the clinical efficacy of adrenocorticotropin in joint diseases, AP1189 was tested in experimental inflammatory arthritis, where this biased agonist afforded significant reduction of macroscopic and histological parameters of joint disruption. "
2.	Arthritis (Polyarthritis) 04/01/2015 - "Finally, given the clinical efficacy of adrenocorticotropin in joint diseases, AP1189 was tested in experimental inflammatory arthritis, where this biased agonist afforded significant reduction of macroscopic and histological parameters of joint disruption. "
3.	Peritonitis 04/01/2015 - "In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ∼3-fold. "
4.	Inflammation (Inflammations) 04/01/2015 - "In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ∼3-fold. "

Related Drugs and Biologics

1.	Adrenocorticotropic Hormone (ACTH)