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AAP1742

Cyclin-Dependent Kinase 9 inhibitor; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Azo Compounds: 333
  - AAP1742: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - AAP1742: 1

Experts

1.	Cankař, Petr: 1 article (10/2014)
2.	Hušková, Zlata: 1 article (10/2014)
3.	Jorda, Radek: 1 article (10/2014)
4.	Kryštof, Vladimír: 1 article (10/2014)
5.	Navrátilová, Jana: 1 article (10/2014)
6.	Schütznerová, Eva: 1 article (10/2014)
7.	Strnad, Miroslav: 1 article (10/2014)

Related Diseases

1.	Multiple Myeloma 10/01/2014 - "Here, we describe a novel member, AAP1742 (CDK9 inhibition with IC(50) = 0.28 μm), that reduces the viability of multiple myeloma cell lines in low micromolar concentrations. " 10/01/2014 - "Arylazopyrazole AAP1742 inhibits CDKs and induces apoptosis in multiple myeloma cells via Mcl-1 downregulation."