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N,N'- ((6- carboxylato)pyridin- 2- yl)methyl)- 1,2- diaminoethane

structure in first source

Also Known As:

H2 dedpa; H2dedpa

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - N,N'-((6-carboxylato)pyridin-2-yl)methyl)-1,2-diaminoethane: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - N,N'-((6-carboxylato)pyridin-2-yl)methyl)-1,2-diaminoethane: 1

Experts

1.	Adam, Michael J: 1 article (05/2015)
2.	Ferreira, Cara L: 1 article (05/2015)
3.	Lin, Kuo-Shyan: 1 article (05/2015)
4.	Orvig, Chris: 1 article (05/2015)
5.	Pan, Jinhe: 1 article (05/2015)
6.	Patrick, Brian O: 1 article (05/2015)
7.	Ramogida, Caterina F: 1 article (05/2015)
8.	Rebullar, Karla: 1 article (05/2015)
9.	Yapp, Donald T T: 1 article (05/2015)

Related Diseases

1.	Neoplasms (Cancer) 05/18/2015 - "Herein, nitroimidazole (NI) derivatives of H2dedpa and H2CHXdedpa to investigate specific targeting of hypoxic tumor cells are investigated, given that NI can be reduced and retained exclusively in hypoxic cells. "
2.	Hypoxia (Hypoxemia) 05/18/2015 - "Of the four H2dedpa or H2CHXdedpa NI derivatives tested, all showed preferential uptake in hypoxic cells compared to normoxic cells with hypoxic/normoxic ratios as high as 7.9 ± 2.7 after 120 min. The results suggest that these novel bis-alkylated NI-containing H2dedpa and H2CHXdedpa ligands would be ideal candidates for further testing in vivo for PET imaging of hypoxia with (68)Ga. " 05/18/2015 - "Nitroimidazole-Containing H2dedpa and H2CHXdedpa Derivatives as Potential PET Imaging Agents of Hypoxia with (68)Ga."

Related Drugs and Biologics

1.	Nitroimidazoles
2.	Ligands