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3- methoxy- N- p- tolylquinoxalin- 2- carboxamide

a 5-HT3 receptor antagonist that possesses both antidepressant and anxiolytic activities

Also Known As:

QCM-4 compound

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinoxalines: 324
      - 3-methoxy-N-p-tolylquinoxalin-2-carboxamide: 1

Experts

1.	Devadoss, Thangaraj: 1 article (04/2017)
2.	Kurhe, Yeshwant: 1 article (04/2017)
3.	Mahesh, R: 1 article (04/2017)

Related Diseases

1.	Obesity 04/01/2017 - "The present study investigates the effect of a novel 5-HT3 receptor antagonist 3-methoxy-N-p-tolylquinoxalin-2-carboxamide (QCM-4) on several pathogenic markers of depression associated with obesity such as plasma insulin resistance, hippocampal cyclic adenosine monophosphate (cAMP), brain-derived neurotrophic factor (BDNF), serotonin (5-HT) concentrations, hippocampal neuronal damage, and p53 protein expression in high-fat-diet (HFD)-fed mice. "
2.	Insulin Resistance 04/01/2017 - "The present study investigates the effect of a novel 5-HT3 receptor antagonist 3-methoxy-N-p-tolylquinoxalin-2-carboxamide (QCM-4) on several pathogenic markers of depression associated with obesity such as plasma insulin resistance, hippocampal cyclic adenosine monophosphate (cAMP), brain-derived neurotrophic factor (BDNF), serotonin (5-HT) concentrations, hippocampal neuronal damage, and p53 protein expression in high-fat-diet (HFD)-fed mice. "

Related Drugs and Biologics

1.	5-HT3 Serotonin Receptors (5 HT3 Receptor)
2.	Brain-Derived Neurotrophic Factor (BDNF)
3.	Serotonin (5 Hydroxytryptamine)
4.	Proteins (Proteins, Gene)
5.	Adenosine Monophosphate (AMP)