HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

1- (3,4- dihydroxyphenyl)- 2- ((1- mesityl- 1H- imidazo(4,5- c)pyridin- 2- yl)thio)ethanone

structure in first source

Also Known As:

CHEQ-2

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - 1-(3,4-dihydroxyphenyl)-2-((1-mesityl-1H-imidazo(4,5-c)pyridin-2-yl)thio)ethanone: 1
  - Pyridazines: 11
    - 1-(3,4-dihydroxyphenyl)-2-((1-mesityl-1H-imidazo(4,5-c)pyridin-2-yl)thio)ethanone: 1

Experts

1.	Kang, Dongwei: 1 article (07/2014)
2.	Li, Xiao: 1 article (07/2014)
3.	Lin, Xiaoqian: 1 article (07/2014)
4.	Liu, Xinyong: 1 article (07/2014)
5.	Song, Yu'ning: 1 article (07/2014)
6.	Zhan, Peng: 1 article (07/2014)
7.	Zhang, Qingzhu: 1 article (07/2014)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 07/23/2014 - "Moreover, CHEQ-2 triggered S-phase cell cycle arrest in MCF-7, HepG2 and HT-29 cell lines, accompanied by generation of ROS, mitochondrial dysfunction and apoptosis. "
2.	Neoplasms (Cancer) 07/23/2014 - "Besides, oral administration of CHEQ-2 (10 mg/kg) significantly inhibited xenografted human liver tumor growth in nude mice, while demonstrated extremely low toxicity (LD50 > 2000 mg/kg). " 07/23/2014 - "Among them, the most potent molecule was CHEQ-2, which could efficiently inhibit the activities of CDC25A/B enzymes as well as the proliferation of various different types of cancer cell lines in vitro assay. "

Related Drugs and Biologics

1.	Enzymes

Related Therapies and Procedures

1.	Oral Administration