Arylquin 1

binds vimentin; has antineoplastic activity; structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 04/01/2020 - "In the present study, we investigated the molecular mechanisms of arylquin 1 in cancer cell death. " 05/18/2022 - "In a mouse xenograft model, Arylquin 1 treatment diminished the growth of colon tumors after injection of cultured cancer cells. " 05/18/2022 - "The MTT assay was used to detect the viability of SW620 and HCT116 cancer cells treated with Arylquin 1 in a dose-dependent manner in vitro. " 04/01/2020 - "Therefore, our results suggest that arylquin 1 induces non-apoptotic cell death in cancer cells through the induction of LMP." 04/01/2020 - "Arylquin 1 induces morphological changes (cell body shrinkage and cell detachment) and decreases cell viability in various cancer cells. "
2.	Colonic Neoplasms (Colon Cancer) 05/18/2022 - "Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells."