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N- (6- (4- butanoyl- 5- methyl- 1H- pyrazol- 1- yl)pyridazin- 3- yl)- 5- chloro- 1- (2- (4- methylpiperazin- 1- yl)- 2- oxoethyl)- 1H- indole- 3- carboxamide

a platelet aggregation inhibitor with P2Y12 antagonist activity; structure in first source

Also Known As:

SAR216471

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 11
    - N-(6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl)-5-chloro-1-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)-1H-indole-3-carboxamide: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - N-(6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl)-5-chloro-1-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)-1H-indole-3-carboxamide: 1

Experts

1.	Boldron, C: 1 article (09/2014)
2.	Bonnet-Lignon, S: 1 article (09/2014)
3.	Bono, F: 1 article (09/2014)
4.	Delesque-Touchard, N: 1 article (09/2014)
5.	Herbert, J M: 1 article (09/2014)
6.	Lassalle, G: 1 article (09/2014)
7.	Millet, L: 1 article (09/2014)
8.	Pflieger, A M: 1 article (09/2014)
9.	Salel, V: 1 article (09/2014)
10.	Savi, P: 1 article (09/2014)

Related Diseases

1.	Thrombosis (Thrombus) 09/01/2014 - "Pre-clinical study of SAR216471 in a rat shunt thrombosis model demonstrated a dose-dependent antithrombotic activity after oral administration (ED50=6.7 mg/kg). "
2.	Hemorrhage 09/01/2014 - "Finally, the anti-hemostatic effect of SAR216471 and its competitors was investigated in a rat tail bleeding model, revealing a favorable safety profile of SAR216471. "

Related Drugs and Biologics

1.	Hemostatics (Antihemorrhagics)

Related Therapies and Procedures

1.	Oral Administration