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N-(2-fluoropropionyl)duramycin

a PET tracer for visualizing cell death sites caused by duramycin chemotherapy

Also Known As:

((18)F)FPDuramycin; N-(2-18F-fluoropropionyl)duramycin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Bacteriocins: 556
        N-(2-fluoropropionyl)duramycin: 1
  - Bacterial Proteins: 394
    - Bacteriocins: 556
      - N-(2-fluoropropionyl)duramycin: 1

Experts

1.	Du, Kan: 1 article (05/2014)
2.	Hu, Kongzhen: 1 article (05/2014)
3.	Jiang, Shende: 1 article (05/2014)
4.	Liang, Xiang: 1 article (05/2014)
5.	Nie, Dahong: 1 article (05/2014)
6.	Tang, Ganghua: 1 article (05/2014)
7.	Yao, Shaobo: 1 article (05/2014)
8.	Zang, Linquan: 1 article (05/2014)

Related Diseases

1.

Neoplasms (Cancer)

05/01/2014 - "Small-animal PET/CT imaging with [(18)F]FPDuramycin proved to be a successful way to visualize in vivo therapeutic-induced tumor cell death. "
05/01/2014 - "Compared with control cells (viable tumor cells), the in vitro binding of [(18)F]FPDuramycin with apoptotic cells induced by anti-Fas antibody resulted in a doubling increase, while the binding of [(18)F]FPDuramycin with necrotic cells induced by three freeze and thaw cycles resulted in a threefold increase. "
05/01/2014 - "In summary, [(18)F]FPDuramycin seems to be a potential PET probe candidate for noninvasive visualization of in vivo cell death sites induced by chemotherapy in tumors."

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)