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KR-66195

a dipeptidyl dipeptidase IV inhibitor; structure in first source

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Branched-Chain Amino Acids: 2289
    - Valine: 1999
      - KR-66195: 1
  - Essential Amino Acids: 1152
    - Valine: 1999
      - KR-66195: 1
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - Thiazolidines: 105
      - KR-66195: 1

Experts

1.	Ahn, Jin Hee: 1 article (06/2014)
2.	Cha, Bong Soo: 1 article (06/2014)
3.	Choi, Cheol Soo: 1 article (06/2014)
4.	Kang, Eun Seok: 1 article (06/2014)
5.	Kim, Yeon Wook: 1 article (06/2014)
6.	Lee, Byung-Wan: 1 article (06/2014)
7.	Lee, Eun Young: 1 article (06/2014)
8.	Lee, Hyun Chul: 1 article (06/2014)
9.	Oh, Hyunhee: 1 article (06/2014)

Related Diseases

1.	Body Weight (Weight, Body) 06/01/2014 - "KR-66195 markedly increased plasma levels of GLP-1, resulting in the probable improvement in glucose tolerance and reduced body weight and food intake. "
2.	Obesity 06/01/2014 - "A pair-feeding study was performed to investigate the mechanisms of the anti-obesity effects of KR-66195 in DIO mice. " 06/01/2014 - "Thus, KR-66195 might be further developed as a therapeutic drug to treat obesity, as well as diabetes." 06/01/2014 - "Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice."
3.	Weight Gain 06/01/2014 - "These results suggest that KR-66195 prevented weight gain in DIO mice by decreasing food intake, as well as increasing energy expenditure. " 06/01/2014 - "We investigated whether KR-66195, a new synthetic dipeptidyl dipeptidase IV inhibitor, could prevent weight gain, as well as improving glycemic control in diet-induced obese (DIO) and ob/ob mice. "

Related Drugs and Biologics

1.	Glucagon-Like Peptide 1 (GLP 1)
2.	Glucose (Dextrose)
3.	Dipeptidyl-Peptidase IV Inhibitors
4.	dipeptidase

Related Therapies and Procedures

1.	Glycemic Control