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PRS-110

a synthetic peptide that antagonizes MET protein

Also Known As:

89Zr-PRS-110

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Lipocalins: 423
      - PRS-110: 2

Experts

1.	Allersdorfer, Andrea: 2 articles (04/2014 - 11/2013)
2.	Audoly, Laurent: 2 articles (04/2014 - 11/2013)
3.	Hülsmeyer, Martin: 2 articles (04/2014 - 11/2013)
4.	Olwill, Shane A: 2 articles (04/2014 - 11/2013)
5.	Hinner, Marlon J: 1 article (04/2014)
6.	Kosterink, Jos G W: 1 article (04/2014)
7.	Lub-de Hooge, Marjolijn N: 1 article (04/2014)
8.	Nagengast, Wouter B: 1 article (04/2014)
9.	Schröder, Carolien P: 1 article (04/2014)
10.	Terwisscha van Scheltinga, Anton G T: 1 article (04/2014)

Related Diseases

1.

Neoplasms (Cancer)

04/01/2014 - "The aim of this study was to visualize MET expression and analyze biodistribution of (89)Zr-labeled PRS-110 in human tumor-bearing mice. "
04/01/2014 - "PET imaging provides real-time noninvasive information about PRS-110 distribution and tumor accumulation in preclinical models."
04/01/2014 - "In vivo visualization of MET tumor expression and anticalin biodistribution with the MET-specific anticalin 89Zr-PRS-110 PET tracer."
04/01/2014 - "Biodistribution analyses showed a dose-dependent tumor uptake of (89)Zr-PRS-110, with the highest fractional tumor uptake at 10 μg of (89)Zr-PRS-110, with no unlabeled PRS-110. "
11/01/2013 - "In vivo administration of PRS-110 resulted in significant, dose-dependent tumor growth inhibition in ligand-dependent (U87-MG) and ligand-independent (Caki-1) xenograft models. "

Related Drugs and Biologics

1.	Ligands
2.	Dihydrotachysterol (AT 10)