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mollemycin A

an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244)

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - mollemycin A: 1
  - Polyketides: 231
    - mollemycin A: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - mollemycin A: 1
Organic Chemicals: 133
- Lactones: 1549
  - Polyketides: 231
    - mollemycin A: 1

Experts

1.	Blumenthal, Antje: 1 article (03/2014)
2.	Capon, Robert J: 1 article (03/2014)
3.	Gardiner, Donald L: 1 article (03/2014)
4.	Khalil, Zeinab G: 1 article (03/2014)
5.	Piggott, Andrew M: 1 article (03/2014)
6.	Raju, Ritesh: 1 article (03/2014)
7.	Skinner-Adams, Tina S: 1 article (03/2014)

Related Diseases

1.	Malaria 03/21/2014 - "Mollemycin A (1) exhibits exceptionally potent and selective growth inhibitory activity against Gram-positive and Gram-negative bacteria (IC50 10-50 nM) and drug-sensitive (3D7; IC50 7 nM) and multidrug-resistant (Dd2; IC50 9 nM) clones of the malaria parasite Plasmodium falciparum. "