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EEDQ
peptide coupling reagent
Also Known As:
2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline; BC 681; N-carbethoxy-2-ethoxy-1,2-dihydroquinoline; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; 2-ethoxy-1(2H)-quinolinecarboxylic acid, ethyl ester
Networked:
5
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinolines: 146
EEDQ: 5
Related Diseases
1.
Shock
06/01/1999 - "
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline studies on the role of 5-HT1A and 5-HT2 receptors in mediating foot-shock-induced ultrasonic vocalisation in adult rats.
"
06/01/1999 - "
Pretreatment with EEDQ (24 h, subcutaneous [s.c.]) inhibited foot-shock-induced ultrasonic vocalisation (effective dose50=0.95 micromol/kg) and decreased [3H]-8-OH-DPAT and [3H]-ketanserin binding in the brain.
"
2.
Catalepsy
08/25/1987 - "
EEDQ administration also induces catalepsy behavior and impairs ability of animals to remain on an inclined screen.
"
07/01/1994 - "
The results in the EEDQ test were related to the potency to block d-amphetamine-induced hyperlocomotion and the ability to induce bar-test catalepsy in the rat.
"
3.
Hypothermia
07/01/1994 - "
4. Pretreatment with the selective alpha 2-adrenoceptor antagonist, RX 821002 (0.1-3.0 mg kg-1, i.p.) 45 min before EEDQ prevented the loss of alpha 2-adrenoceptors as well as the blockade of medetomide-induced sedation and hypothermia by EEDQ.
"
4.
Glioma (Gliomas)
08/01/1986 - "
Treatment of intact L6 myoblasts or C6 glioma cells with N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) inactivated beta-adrenergic receptors on membranes prepared from these cells.
"
Related Drugs and Biologics
1.
EEDQ
2.
beta Adrenergic Receptors
3.
Ketanserin
4.
Dextroamphetamine (Dexedrine)
5.
2-methoxyidazoxan
6.
hydroxide ion