Tak W Mak Selected Research

Tensins

1/2021	Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy.
3/2009	FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation.

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Tak W Mak Research Topics

Disease

109	Neoplasms (Cancer) 03/2024 - 06/2002
33	Inflammation (Inflammations) 01/2023 - 06/2003
21	Infections 12/2021 - 06/2003
16	Breast Neoplasms (Breast Cancer) 01/2024 - 02/2010
10	Virus Diseases (Viral Diseases) 01/2022 - 02/2007
9	Obesity 12/2021 - 07/2006
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2023 - 02/2010
8	Carcinogenesis 10/2020 - 10/2004
7	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2023 - 09/2003
5	Glioma (Gliomas) 12/2022 - 02/2010
5	Fibrosis (Cirrhosis) 01/2021 - 01/2006
5	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2021 - 07/2002
5	Genomic Instability 06/2016 - 10/2008
5	Hodgkin Disease (Hodgkin's Disease) 09/2004 - 01/2002
4	Aneuploidy (Aneuploid) 10/2019 - 01/2016
4	Polyploidy 10/2019 - 02/2009
4	Hypoxia (Hypoxemia) 08/2017 - 05/2011
4	Parkinson Disease (Parkinson's Disease) 06/2015 - 10/2006
4	Necrosis 06/2015 - 03/2004
4	Insulin Resistance 01/2015 - 04/2010
3	Hematologic Neoplasms (Hematological Malignancy) 12/2023 - 02/2016
3	Hyperplasia 01/2023 - 02/2005
3	Hepatitis 01/2022 - 03/2004
3	Nephritis 01/2022 - 05/2012
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 07/2015
3	Lung Neoplasms (Lung Cancer) 10/2019 - 01/2009
3	Colitis 06/2019 - 08/2011
3	Vesicular Stomatitis 01/2018 - 05/2004
3	Autoimmune Diseases (Autoimmune Disease) 01/2017 - 12/2007
3	Neuroblastoma 11/2013 - 04/2011
3	Glioblastoma (Glioblastoma Multiforme) 08/2012 - 02/2010
3	Lymphoma (Lymphomas) 08/2010 - 06/2003
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2023 - 01/2021
2	Hepatocellular Carcinoma (Hepatoma) 10/2023 - 07/2015
2	Mesothelioma 01/2023 - 10/2020
2	Leukemia 12/2022 - 02/2010
2	Hypertension (High Blood Pressure) 12/2021 - 12/2020
2	COVID-19 12/2021 - 12/2020

Drug/Important Bio-Agent (IBA)

26	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2002
25	CytokinesIBA 01/2023 - 01/2002
16	Phosphotransferases (Kinase)IBA 12/2023 - 07/2002
15	Lipocalin-2IBA 08/2017 - 02/2006
12	Transcription Factors (Transcription Factor)IBA 12/2022 - 03/2005
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 11/2005
9	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 12/2022 - 02/2010
9	EnzymesIBA 12/2022 - 05/2005
9	Protein Isoforms (Isoforms)IBA 10/2017 - 10/2008
7	AntioxidantsIBA 01/2021 - 10/2006
7	Antiviral Agents (Antivirals)IBA 01/2019 - 02/2007
6	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2022 - 05/2005
5	2- (3- (4- ((2,6- dimethylmorpholino)methyl)styryl)- 1H- indazol- 6- yl)- 5'- methoxyspiro(cyclopropane- 1,3'- indolin)- 2'- oneIBA 12/2023 - 08/2014
5	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021 - 04/2003
5	ChemokinesIBA 01/2021 - 01/2012
5	LipidsIBA 01/2017 - 04/2003
5	Interleukin-6 (Interleukin 6)IBA 02/2015 - 03/2005
4	RNA (Ribonucleic Acid)IBA 04/2024 - 01/2018
4	CarcinogensIBA 10/2023 - 10/2008
4	Biomarkers (Surrogate Marker)IBA 12/2022 - 07/2015
4	AntibodiesIBA 01/2020 - 05/2012
4	Glutathione (Reduced Glutathione)IBA 11/2019 - 02/2015
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 10/2004
4	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 09/2003
4	Small Interfering RNA (siRNA)IBA 07/2017 - 05/2011
4	Interleukin-7 (Interleukin 7)IBA 02/2011 - 02/2008
4	NF-kappa B (NF-kB)IBA 01/2006 - 06/2003
4	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 03/2005 - 04/2003
3	Estrogen ReceptorsIBA 01/2024 - 03/2011
3	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 10/2023 - 01/2019
3	LipopolysaccharidesIBA 01/2022 - 03/2005
3	Arginine (L-Arginine)FDA Link 01/2022 - 07/2013
3	Type I Tumor Necrosis Factor ReceptorsIBA 01/2022 - 12/2007
3	CFI-402257IBA 01/2022 - 01/2017
3	Interleukin-17 (Interleukin 17)IBA 01/2021 - 04/2009
3	Caspase 3 (Caspase-3)IBA 01/2021 - 12/2010
3	Ligases (Synthetase)IBA 03/2019 - 12/2007
3	Interferon Type IIBA 01/2018 - 05/2015
3	SiderophoresIBA 04/2017 - 04/2009
3	Insulin (Novolin)FDA Link 01/2017 - 02/2005
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2017 - 05/2013
3	Tamoxifen FDA LinkGeneric 01/2017 - 12/2012
3	Glucose (Dextrose)FDA LinkGeneric 02/2016 - 04/2010
3	isocitric acid (isocitrate)IBA 01/2016 - 08/2012
3	Adenosine Triphosphate (ATP)IBA 11/2013 - 04/2007
3	Oxidoreductases (Dehydrogenase)IBA 07/2013 - 04/2007
3	LigandsIBA 01/2010 - 09/2004
2	Histone DemethylasesIBA 01/2024 - 03/2011
2	Cholinergic Agents (Cholinergics)IBA 10/2023 - 01/2023
2	HMGB1 Protein (HMG1)IBA 01/2023 - 10/2020
2	AsbestosIBA 01/2023 - 10/2020
2	InterferonsIBA 12/2022 - 09/2012
2	NucleotidesIBA 12/2022 - 10/2016
2	Choline (Choline Chloride)IBA 01/2022 - 10/2014
2	Aurora Kinase AIBA 01/2022 - 11/2015
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022 - 09/2003
2	Glutamine (L-Glutamine)FDA Link 12/2021 - 02/2016
2	Plasminogen Activator Inhibitor 1IBA 12/2021 - 12/2020

Therapy/Procedure

31	Therapeutics 12/2023 - 01/2005
9	Immunotherapy 03/2024 - 05/2009
5	Ligation 10/2019 - 05/2013
3	Drug Therapy (Chemotherapy) 01/2019 - 03/2010