Jhanelle E Gray Selected Research

Thrombocytopenia (Thrombopenia)

12/2015

A first-in-human phase I dose-escalation, pharmacokinetic, and pharmacodynamic evaluation of intravenous LY2090314, a glycogen synthase kinase 3 inhibitor, administered in combination with pemetrexed and carboplatin.

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Jhanelle E Gray Research Topics

Disease

59	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2024 - 11/2010
32	Neoplasms (Cancer) 11/2023 - 11/2010
17	Disease Progression 02/2024 - 11/2017
17	Lung Neoplasms (Lung Cancer) 01/2024 - 01/2013
6	Fatigue 01/2022 - 01/2018
6	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2019 - 01/2013
4	Nausea 04/2023 - 08/2018
3	Brain Neoplasms (Brain Tumor) 11/2022 - 06/2017
3	Neoplasm Metastasis (Metastasis) 10/2022 - 11/2017
3	Pneumonia (Pneumonitis) 01/2022 - 11/2017
3	Vomiting 11/2019 - 01/2018
3	Melanoma (Melanoma, Malignant) 01/2017 - 01/2013
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2024 - 01/2021
2	Chest Pain (Chest Pains) 01/2020 - 12/2019
2	Body Weight (Weight, Body) 12/2018 - 11/2017
2	Adenocarcinoma of Lung 12/2018 - 12/2016
1	Small Cell Carcinoma 04/2024
1	Acquired Immunodeficiency Syndrome (AIDS) 02/2024
1	Inflammation (Inflammations) 01/2024
1	Hypothyroidism 04/2023
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 04/2023
1	COVID-19 02/2023
1	Vaccinia 01/2023
1	Carcinoma (Carcinomatosis) 10/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2022
1	Hypoxia (Hypoxemia) 01/2021
1	Fibrosarcoma 01/2020
1	Cough 12/2019
1	Triple Negative Breast Neoplasms 01/2019
1	Injection Site Reaction 12/2018
1	Carcinogenesis 11/2018

Drug/Important Bio-Agent (IBA)

12	osimertinibIBA 01/2024 - 11/2018
11	pembrolizumabIBA 01/2024 - 02/2018
11	Immune Checkpoint InhibitorsIBA 11/2022 - 12/2015
10	ErbB Receptors (EGF Receptor)IBA 02/2024 - 11/2010
10	Tyrosine Kinase InhibitorsIBA 02/2024 - 11/2010
10	durvalumabIBA 01/2024 - 11/2017
10	PlatinumIBA 10/2023 - 01/2016
5	NivolumabIBA 01/2024 - 01/2022
5	Biomarkers (Surrogate Marker)IBA 04/2023 - 11/2013
4	Circulating Tumor DNAIBA 02/2024 - 01/2022
4	Pemetrexed (MTA)FDA Link 10/2023 - 12/2015
4	B7-H1 AntigenIBA 01/2021 - 11/2017
4	VaccinesIBA 03/2019 - 01/2013
3	IpilimumabIBA 01/2024 - 07/2023
3	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2019
3	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2020 - 03/2014
3	Histone Deacetylase InhibitorsIBA 11/2019 - 03/2014
2	AfatinibIBA 11/2023 - 01/2019
2	Carboplatin (JM8)FDA LinkGeneric 10/2023 - 12/2015
2	Vorinostat FDA Link 04/2023 - 11/2019
2	Docetaxel (Taxotere)FDA Link 01/2023 - 01/2023
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022 - 01/2018
2	Neoplasm Antigens (Tumor Antigens)IBA 06/2021 - 03/2019
2	Gefitinib (Iressa)FDA Link 01/2020 - 01/2019
2	Anaplastic Lymphoma KinaseIBA 01/2020 - 01/2018
2	Glycoproteins (Glycoprotein)IBA 01/2019 - 11/2018
2	Mucin-1 (CA 15-3 Antigen)IBA 11/2018 - 01/2013
2	adavosertibIBA 01/2017 - 01/2016
1	binimetinibIBA 05/2024
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 05/2024
1	encorafenibIBA 05/2024
1	Gonadal Steroid Hormones (Sex Hormones)IBA 03/2024
1	Dehydroepiandrosterone (DHEA)IBA 03/2024
1	zimberelimabIBA 01/2024
1	Immunoglobulins (Immunoglobulin)IBA 01/2024
1	Cisplatin (Platino)FDA LinkGeneric 10/2023
1	trametinibIBA 01/2023
1	SteroidsIBA 01/2022
1	spartalizumabIBA 01/2022
1	RamucirumabIBA 01/2022
1	Adenosine (Adenocard)FDA LinkGeneric 01/2022
1	Alanine (L-Alanine)FDA Link 01/2022
1	LigandsIBA 01/2022
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022
1	Recombinant DNA (Recombinant DNA Research)IBA 01/2021
1	Carbonic Anhydrase IXIBA 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2020
1	Glycerol KinaseIBA 01/2020
1	Formaldehyde (Formol)FDA Link 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 11/2019
1	thiamine triphosphorate (TTP)IBA 01/2019
1	Dasatinib (BMS 354825)FDA Link 01/2019
1	CD40 Ligand (CD40L)IBA 12/2018
1	Chemokine CCL21IBA 12/2018
1	AntiemeticsIBA 08/2018
1	Transaminases (Aminotransferases)IBA 01/2018
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2018
1	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2018
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 10/2017
1	Irinotecan (Camptosar)FDA LinkGeneric 10/2017
1	Immunoconjugates (Immunoconjugate)IBA 10/2017
1	sacituzumab govitecanIBA 10/2017

Therapy/Procedure

24	Therapeutics 05/2024 - 11/2010
17	Immunotherapy 03/2024 - 01/2013
15	Drug Therapy (Chemotherapy) 01/2024 - 07/2011
6	Chemoradiotherapy 01/2022 - 11/2017
3	Radiotherapy 01/2022 - 11/2017