William J Craigen Selected Research

N,N-dimethylarginine (asymmetric dimethylarginine)

4/2012

Restoration of impaired nitric oxide production in MELAS syndrome with citrulline and arginine supplementation.

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William J Craigen Research Topics

Disease

14	Mitochondrial Diseases (Mitochondrial Disease) 07/2017 - 04/2002
6	MELAS Syndrome (Syndrome, MELAS) 04/2016 - 04/2012
4	Stroke (Strokes) 03/2014 - 04/2012
4	Lactic Acidosis 03/2014 - 11/2012
3	Neoplasms (Cancer) 01/2020 - 01/2015
3	Neurodevelopmental Disorders 01/2020 - 01/2017
3	Intellectual Disability (Idiocy) 01/2019 - 02/2017
3	Glycogen Storage Disease Type IV (Andersen's Disease) 12/2015 - 11/2011
2	Epilepsy (Aura) 01/2023 - 07/2010
2	Inborn Errors Metabolism (Inborn Errors of Metabolism) 11/2018 - 01/2011
2	Mitochondrial Encephalomyopathies (Mitochondrial Encephalomyopathy) 01/2016 - 02/2014
2	VLCAD deficiency 11/2015 - 12/2010
2	Muscular Dystrophies (Muscular Dystrophy) 04/2014 - 11/2005
2	Muscular Diseases (Myopathy) 03/2014 - 11/2012
2	Inborn Genetic Diseases (Disease, Hereditary) 09/2013 - 08/2013
2	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 12/2011 - 11/2005
1	Hydrocephalus (Hydrocephaly) 01/2023
1	Quadriplegia (Spastic Quadriplegia) 01/2023
1	Megalencephaly 01/2023
1	Undiagnosed Diseases 01/2021
1	Developmental Disabilities (Developmental Disability) 01/2021
1	Glycogen Storage Disease Type II (Pompe's Disease) 01/2021
1	Ischemia 10/2020
1	Kidney Neoplasms (Kidney Cancer) 01/2020
1	Leigh Disease (Leigh's Disease) 01/2020
1	Gamma aminobutyric acid transaminase deficiency 01/2019
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 12/2018
1	Metabolic Diseases (Metabolic Disease) 11/2018
1	Phenylketonurias (Phenylketonuria) 11/2018
1	Status Epilepticus (Complex Partial Status Epilepticus) 07/2017
1	Deafness (Deaf Mutism) 02/2017
1	Propionic Acidemia 01/2017
1	Cakut 01/2017
1	Methylmalonic acidemia 01/2016
1	Adult Form Polyglucosan Body Disease 12/2015
1	Hypoxia (Hypoxemia) 01/2015
1	Inflammation (Inflammations) 01/2015
1	Insulin Resistance 09/2014
1	Mitochondrial encephalopathy 09/2013
1	Glycogen Storage Disease (Glycogenosis) 02/2013
1	Citrullinemia 06/2012
1	VDAC Deficiency 06/2012

Drug/Important Bio-Agent (IBA)

8	Mitochondrial DNA (mtDNA)IBA 01/2016 - 10/2004
6	Arginine (L-Arginine)FDA Link 04/2016 - 01/2003
6	EnzymesIBA 01/2016 - 12/2006
5	CitrullineIBA 04/2016 - 04/2012
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2016 - 04/2012
4	Adenosine Triphosphate (ATP)IBA 10/2020 - 05/2006
3	Therapeutic UsesIBA 04/2016 - 04/2012
3	GlycogenIBA 02/2013 - 01/2011
3	Proteins (Proteins, Gene)FDA Link 12/2011 - 02/2005
2	Adenosine Triphosphatases (ATPase)IBA 01/2020 - 02/2017
2	ChromatinIBA 01/2019 - 06/2017
2	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2017 - 01/2017
2	NucleotidesIBA 01/2017 - 05/2006
2	IsotopesIBA 04/2016 - 04/2012
2	Succinate-CoA Ligases (Succinyl Coenzyme A Synthetases)IBA 01/2016 - 02/2014
2	Ligases (Synthetase)IBA 01/2016 - 02/2014
2	1,4-alpha-Glucan Branching Enzyme (Glycogen Branching Enzyme)IBA 12/2015 - 11/2011
2	Glucose (Dextrose)FDA LinkGeneric 09/2014 - 02/2007
2	DystrophinIBA 12/2011 - 11/2005
1	Protein Kinases (Protein Kinase)IBA 01/2023
1	Methotrexate (Mexate)FDA LinkGeneric 01/2021
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2021
1	Rituximab (Mabthera)FDA Link 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Retinaldehyde (Retinal)IBA 01/2020
1	Voltage-Dependent Anion ChannelsIBA 01/2020
1	2-pyrrolidoneIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	succinimideIBA 01/2019
1	Histones (Histone)IBA 01/2019
1	fucokinaseIBA 12/2018
1	Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)IBA 11/2018
1	Adenosine Monophosphate (AMP)IBA 11/2018
1	Poly (ADP-Ribose) Polymerase-1IBA 07/2017
1	Transcription Factors (Transcription Factor)IBA 06/2017
1	ATP dependent 26S protease (26S proteasome)IBA 02/2017
1	propionylcarnitineIBA 01/2017
1	hydracrylic acidIBA 01/2017
1	2-methylcitric acidIBA 01/2017
1	6-propylchromone-2-carboxylic acid (PCCA)IBA 01/2017
1	AcidsIBA 01/2017
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2015
1	Long-Chain Acyl-CoA Dehydrogenase (Long-Chain-Acyl-Coenzyme A Dehydrogenase)IBA 11/2015
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2015
1	Oxygen (Dioxygen)IBA 01/2015
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2015
1	Insulin (Novolin)FDA Link 09/2014
1	Dystroglycans (Dystroglycan)IBA 04/2014
1	Methylmalonic AcidIBA 02/2014
1	A-Form DNA (A-DNA)IBA 08/2013
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 11/2012
1	Reactive Nitrogen SpeciesIBA 11/2012
1	Protein Isoforms (Isoforms)IBA 06/2012
1	polyglucosanIBA 06/2012
1	Urea (Carbamide)FDA LinkGeneric 06/2012

Therapy/Procedure

1	Enzyme Replacement Therapy 01/2021
1	Drug Therapy (Chemotherapy) 01/2015
1	Long-Term Care 06/2012