Philippe Connes Selected Research

Nitrites

12/2018

Hydroxyurea therapy modulates sickle cell anemia red blood cell physiology: Impact on RBC deformability, oxidative stress, nitrite levels and nitric oxide synthase signalling pathway.

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Philippe Connes Research Topics

Disease

53	Sickle Cell Anemia (Hemoglobin S Disease) 12/2023 - 01/2008
17	Sickle Cell Trait 12/2023 - 12/2005
13	Hemolysis 12/2023 - 05/2013
10	Inflammation (Inflammations) 12/2022 - 01/2013
8	Hypoxia (Hypoxemia) 12/2022 - 09/2004
8	Hemoglobin SC Disease (Disease, Hemoglobin SC) 06/2021 - 01/2014
7	alpha-Thalassemia 01/2022 - 07/2005
6	Thalassemia 12/2023 - 01/2014
6	Anemia 01/2022 - 01/2013
6	Acute Chest Syndrome 01/2020 - 01/2013
3	Hemorrhage 02/2024 - 11/2020
3	Pain (Aches) 01/2022 - 11/2011
3	Glucosephosphate Dehydrogenase Deficiency 09/2020 - 03/2017
3	Hypertension (High Blood Pressure) 12/2018 - 01/2013
3	Hemoglobinopathies 01/2017 - 01/2008
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 11/2022
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 01/2022
2	Infections 01/2022 - 01/2021
2	Macular Degeneration (Age-Related Maculopathy) 01/2021 - 12/2019
2	Vascular Diseases (Vascular Disease) 01/2021 - 01/2018
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2021 - 01/2020
2	Dehydration (Water Stress) 01/2020 - 01/2019
1	Hereditary Spherocytosis 04/2024
1	Hemarthrosis 02/2024
1	Hemophilia A (Haemophilia) 02/2024
1	Joint Diseases (Joint Disease) 02/2024
1	Thrombosis (Thrombus) 01/2023
1	Atrophy 11/2022
1	Ischemia 01/2021
1	Thrombophilia 11/2020
1	Atherosclerotic Plaque (Atheroma) 04/2020
1	Carotid Stenosis (Carotid Artery Stenosis) 04/2020
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020

Drug/Important Bio-Agent (IBA)

27	Hemoglobins (Hemoglobin)IBA 12/2023 - 11/2007
14	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2023 - 01/2010
12	Oxygen (Dioxygen)IBA 11/2023 - 08/2009
10	Hydroxyurea (Hydrea)FDA LinkGeneric 12/2023 - 10/2015
9	Biomarkers (Surrogate Marker)IBA 02/2024 - 11/2015
8	Sickle HemoglobinIBA 12/2023 - 08/2009
6	GlobinsIBA 12/2023 - 01/2011
4	Fetal Hemoglobin (Hemoglobin F)IBA 12/2023 - 01/2013
4	Lactic Acid (Lactate)FDA LinkGeneric 01/2023 - 09/2004
4	alpha-GlobinsIBA 01/2021 - 08/2010
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 05/2016
3	CytokinesIBA 01/2021 - 01/2018
3	AntioxidantsIBA 09/2020 - 05/2016
3	LipidsIBA 04/2020 - 01/2013
3	Advanced Glycation End ProductsIBA 01/2019 - 11/2015
3	Nitric Oxide Synthase (NO Synthase)IBA 12/2018 - 02/2015
3	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 11/2016 - 01/2007
2	Factor IX (Coagulation Factor IX)FDA LinkGeneric 02/2024 - 12/2023
2	Hemostatics (Antihemorrhagics)IBA 12/2023 - 11/2020
2	CalciumIBA 01/2023 - 04/2020
2	PhosphatidylserinesIBA 01/2023 - 01/2020
2	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2019
2	HDL CholesterolIBA 11/2022 - 03/2018
2	CholesterolIBA 11/2022 - 01/2020
2	SelectinsIBA 01/2022 - 01/2008
2	Hemoglobin CIBA 05/2021 - 06/2014
2	Biological FactorsIBA 01/2021 - 01/2013
2	Advanced Oxidation Protein Products (AOPP)IBA 09/2020 - 11/2016
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2019
2	hemoglobin AAIBA 12/2019 - 07/2005
2	Triglycerides (Triacylglycerol)IBA 03/2018 - 01/2013
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2008 - 01/2007
1	Chemokine CXCL12IBA 02/2024
1	Factor VIII (Coagulation Factor VIII)IBA 02/2024
1	Cartilage Oligomeric Matrix ProteinIBA 02/2024
1	Liver X ReceptorsIBA 01/2024
1	Ion Channels (Ion Channel)IBA 12/2023
1	Tricarboxylic AcidsIBA 01/2023
1	Succinic Acid (Succinate)IBA 01/2023
1	FumaratesIBA 01/2023
1	malic acid (malate)IBA 01/2023
1	Pyruvate KinaseIBA 01/2023
1	Blood Proteins (Serum Proteins)IBA 12/2022
1	tetracarboxyphenylporphineIBA 12/2022
1	Retinaldehyde (Retinal)IBA 11/2022
1	HLA-DR Antigens (HLA-DR)IBA 01/2022
1	Carboxylic AcidsIBA 01/2022
1	Pyruvic Acid (Pyruvate)IBA 01/2022
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2022
1	Membrane LipidsIBA 01/2022
1	P-SelectinIBA 01/2022
1	N 30IBA 01/2022
1	lysophosphatidic acidIBA 01/2021
1	Edetic Acid (EDTA)FDA Link 01/2021
1	Antigen Receptors (Antigen Receptor)IBA 01/2020
1	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 01/2020
1	ChemokinesIBA 01/2020
1	Heme (Haem)IBA 01/2020
1	AlarminsIBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	C-Reactive ProteinIBA 10/2019
1	DiamideIBA 01/2019

Therapy/Procedure

8	Therapeutics 06/2021 - 01/2014
2	Aftercare (After-Treatment) 03/2015 - 12/2012
1	Splenectomy 04/2024
1	Blood Transfusion (Blood Transfusions) 11/2020
1	Carotid Endarterectomy 04/2020