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Langerhans Cell Sarcoma Summary

Description: Rare malignant neoplasm of dendritic LANGERHANS CELLS exhibiting atypical cytology, frequent mitoses, and aggressive clinical behavior. They can be distinguished from other histiocytic and dendritic proliferations by immunohistochemical and ultrastructure studies. Cytologically benign proliferations of Langerhans cells are called LANGERHANS CELL HISTIOCYTOSIS.

Also Known As: Langerhans Cell Sarcomas; Sarcoma, Langerhans Cell; Sarcomas, Langerhans Cell

Networked: 14 relevant articles (0 outcomes, 3 trials/studies) for this Disease

Key Drugs and Agents for Langerhans Cell Sarcoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. DNA (Deoxyribonucleic Acid) : 1 study in 2 results : IBA
  2. Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule) : 1 study in 1 result : IBA
  3. Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain) : 1 study in 1 result : IBA
  4. S100 Proteins (S 100 Protein) : 2 results : IBA
  5. Cladribine : 1 result : FDA 3 Generic
  6. Proteins (Proteins, Gene) : 1 result : IBA
  7. Antigens : 1 result : IBA
  8. DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN) : 1 result : IBA
  9. imatinib (Gleevec) : 1 result : FDA 3
  10. fascin : 1 result : IBA
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Diseases Related to Langerhans Cell Sarcoma

  1. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
  2. Hairy Cell Leukemia
  3. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
  4. Neoplasms (Cancer)
  5. Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell)

Key Therapies for Langerhans Cell Sarcoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 3 results
  2. Liver Transplantation : 1 result
  3. Transplantation (Transplant Recipients) : 1 result
  4. Radiotherapy : 1 result

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