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Toll-Like Receptors (Toll-Like Receptor) Summary

Description: A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.

Also Known As: Toll-Like Receptor; Receptor, Toll-Like; Receptors, Toll Like; Toll Like Receptor; Toll Like Receptors Show All >>

Networked: 4685 relevant articles (71 outcomes, 401 trials/studies) for this Bio-Agent

Key Diseases for which Toll-Like Receptors is Relevant

  1. Infection : 17 outcomes 63 studies in 1071 results
  2. Neoplasms (Cancer) : 12 outcomes 32 studies in 392 results
  3. Inflammation : 10 outcomes 41 studies in 729 results
  4. Colitis : 4 outcomes 3 studies in 35 results
  5. Porcine Reproductive and Respiratory Syndrome (PRRS) : 3 outcomes 9 studies in 289 results
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Drugs Related to Toll-Like Receptors

  1. Ligands
  2. Antigens
  3. Vaccines
  4. Cytokines
  5. Interleukins
  6. Interleukin-6 (Interleukin 6)
  7. Messenger RNA (mRNA)
  8. ProMune (CpG 7909)
  9. bis(4-hydroxycinnamoyl)methane
  10. Pattern Recognition Receptors
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Therapies Related to Toll-Like Receptors

  1. Immunotherapy
  2. Drug Therapy (Chemotherapy)
  3. Liver Transplantation
  4. Resuscitation
  5. Therapeutics
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