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Plectin Summary

Description: A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and MICROFILAMENTS and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.

Also Known As: 500-kDa HD1 Protein; Hemidesmosomal Protein HD1; 500 kDa HD1 Protein; HD1 Protein, 500-kDa; HD1, Hemidesmosomal Protein

Networked: 175 relevant articles (0 outcomes, 10 trials/studies) for this Bio-Agent

Key Diseases for which Plectin is Relevant

  1. Muscular Dystrophies (Muscular Dystrophy) : 2 studies in 68 results
  2. Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara) : 1 study in 57 results
  3. Bullous Pemphigoid (Pemphigoid) : 1 study in 38 results
  4. Neoplasms (Cancer) : 1 study in 13 results
  5. Hepatocellular Carcinoma (Hepatoma) : 1 study in 7 results
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Drugs Related to Plectin

  1. Antigens
  2. Desmoplakins (Desmoplakin)
  3. envoplakin
  4. Vimentin
  5. Carrier Proteins (Binding Protein)
  6. Phosphotransferases (Kinase)
  7. Proteins (Proteins, Gene)
  8. Desmin
  9. Antibodies
  10. Integrin beta4
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Therapies Related to Plectin


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