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Ovotesticular Disorders of Sex Development Summary

Description: Conditions of sexual ambiguity in which the individual possesses gonadal tissues of both sexes, tissues from the OVARY and the TESTIS. There can be a testis on one side and an ovary on the other (lateral), or there may be combined ovarian and testicular tissue (ovotestes) on each side (bilateral). The karyotype may be 46,XX; 46,XY; or a mosaic of 46,XX/46,XY. These disorders have historically been called true hermaphroditism.

Also Known As: Familial True Hermaphroditism; Familial XX True Hermaphroditism; Ovotesticular DSD; True Hermaphroditism; DSD, Ovotesticular Show All >>

Networked: 56 relevant articles (0 outcomes, 7 trials/studies) for this Disease

Key Drugs and Agents for Ovotesticular Disorders of Sex Development

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. H-Y Antigen : 2 studies in 5 results : IBA
  2. Complement System Proteins (Complement) : 1 study in 4 results : IBA
  3. Testosterone (Sustanon) : 1 study in 3 results : FDA 13
  4. Androgen Receptors (Androgen Receptor) : 1 study in 2 results : IBA
  5. Protein Isoforms (Isoforms) : 1 study in 1 result : IBA
  6. Nitric Oxide Synthase (NO Synthase) : 1 study in 1 result : IBA
  7. Mosaic variegated aneuploidy syndrome : 1 study in 1 result : IBA
  8. N 30 : 1 study in 1 result : IBA
  9. XXY syndrome : 6 results : IBA
  10. Oxidoreductases : 2 results : IBA
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Diseases Related to Ovotesticular Disorders of Sex Development

  1. Gonadal Dysgenesis (Gonadal Agenesis)
  2. Disorders of Sex Development (Intersexuality)
  3. XX Disorders of Sex Development 46 (Female Pseudohermaphroditism)
  4. Androgen-Insensitivity Syndrome (Testicular Feminization)
  5. Mixed Gonadal Dysgenesis
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Key Therapies for Ovotesticular Disorders of Sex Development

Efficacy Chart >>
  1. Laparotomy : 4 results
  2. Orchiopexy : 2 results
  3. Transplantation (Transplant Recipients) : 1 result
  4. Ovariectomy (Oophorectomy) : 1 result
  5. Orchiectomy (Orchidectomy) : 1 result
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