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Type I Tumor Necrosis Factor Receptors Summary

Description: A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.

Also Known As: Receptors, Tumor Necrosis Factor, Type I; CD 120a Antigen; CD120a Antigen; TNFR p60; TNFR-I Show All >>

Networked: 627 relevant articles (29 outcomes, 73 trials/studies) for this Bio-Agent

Key Diseases for which Type I Tumor Necrosis Factor Receptors is Relevant

  1. Infection : 5 outcomes 4 studies in 53 results
  2. Inflammation : 3 outcomes 5 studies in 88 results
  3. Ischemia : 2 outcomes 3 studies in 13 results
  4. Neoplasms (Cancer) : 2 outcomes 2 studies in 61 results
  5. Demyelinating Diseases (Demyelinating Disease) : 2 outcomes 1 study in 5 results
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Drugs Related to Type I Tumor Necrosis Factor Receptors

  1. Type II Tumor Necrosis Factor Receptors
  2. Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
  3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  4. NF-kappa B (NF-kB)
  5. Interleukin-1 (Interleukin 1)
  6. Small Interfering RNA (siRNA)
  7. Turpentine
  8. Caspases
  9. Protein Kinases (Protein Kinase)
  10. Perforin
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Therapies Related to Type I Tumor Necrosis Factor Receptors

  1. Ligation
  2. Moxibustion
  3. Transplants (Transplant)
  4. Transplantation (Transplant Recipients)
  5. Bone Marrow Transplantation (Transplantation, Bone Marrow)
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