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Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase) Summary

Description: A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.

Also Known As: Ubiquitin-Protein Ligase; E3 Ligase; E3 Ubiquitin Ligase; Ubiquitin Ligase E3; Ubiquitin-Protein Ligase E3 Show All >>

Networked: 1227 relevant articles (5 outcomes, 77 trials/studies) for this Bio-Agent

Key Diseases for which Ubiquitin-Protein Ligases is Relevant

  1. Neoplasms (Cancer) : 2 outcomes 24 studies in 347 results
  2. Anoxia (Hypoxia) : 1 outcome 5 studies in 76 results
  3. Pneumonia (Pneumonitis) : 1 outcome 1 study in 3 results
  4. Lafora Disease : 1 outcome in 10 results
  5. Heart Diseases (Heart Disease) : 1 outcome in 1 result
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Drugs Related to Ubiquitin-Protein Ligases

  1. Proteins (Proteins, Gene)
  2. Ubiquitin
  3. Proteasome Endopeptidase Complex (Proteasome)
  4. Transcription Factors (Transcription Factor)
  5. Staphylococcal Protein A (A, Protein)
  6. Ligases
  7. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  8. polyglucosan
  9. Cyclin D1
  10. DNA (Deoxyribonucleic Acid)
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Therapies Related to Ubiquitin-Protein Ligases

  1. Therapeutics
  2. Drug Therapy (Chemotherapy)
  3. Radiotherapy
  4. Castration
  5. Heterologous Transplantation (Xenotransplantation)
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