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5-HT3 Serotonin Receptors
(5 HT3 Receptor)
Summary
Description:
A subclass of serotonin receptors that form cation channels and mediate signal transduction by depolarizing the cell membrane. The cation channels are formed from 5 receptor subunits. When stimulated the receptors allow the selective passage of SODIUM; POTASSIUM; and CALCIUM.
Also Known As:
5 HT3 Receptor; Receptors, Serotonin, 5-HT3; 5-HT3 Receptor; 5-Hydroxytryptamine-3 Receptor; Receptor, Serotonin 3 Show All >>
Networked: 669
relevant articles (108 outcomes,
104 trials/studies)
for this Bio-Agent
Key Diseases for which 5-HT3 Serotonin Receptors is
Relevant
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Vomiting
:
55 outcomes 44 studies in 294 results
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Nausea
:
27 outcomes 23 studies in 144 results
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Postoperative Nausea and Vomiting (PONV)
:
12 outcomes 7 studies in 43 results
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Neoplasms (Cancer)
:
8 outcomes 12 studies in 56 results
-
Pain (Aches)
:
8 outcomes 8 studies in 40 results
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Drugs Related to 5-HT3 Serotonin Receptors
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Ondansetron (Zofran)
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Cisplatin (Platino)
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Dexamethasone (Maxidex)
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Granisetron (Kytril)
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tropisetron (Navoban)
-
palonosetron (Aloxi)
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Serotonin (5 Hydroxytryptamine)
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alosetron (Lotronex)
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aprepitant (Emend)
-
azasetron
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Therapies Related to 5-HT3 Serotonin Receptors
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Drug Therapy (Chemotherapy)
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Craniotomy
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Radiotherapy
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Adjuvant Chemotherapy
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Fluid Therapy (Oral Rehydration Therapy)
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