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Endothelin A Receptor Summary

Description: A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high affinity for ENDOTHELIN-1 and ENDOTHELIN-2.

Also Known As: Receptor, Endothelin A; Receptor, Endothelin-1; Endothelin-1 Receptor; Receptor, Endothelin 1; Receptors, Endothelin A Show All >>

Networked: 373 relevant articles (35 outcomes, 58 trials/studies) for this Bio-Agent

Key Diseases for which Endothelin A Receptor is Relevant

  1. Pulmonary Hypertension (Ayerza Syndrome) : 7 outcomes 5 studies in 31 results
  2. Reperfusion Injury : 4 outcomes 2 studies in 13 results
  3. Prostatic Neoplasms (Prostate Cancer) : 3 outcomes 7 studies in 27 results
  4. Ischemia : 3 outcomes 4 studies in 18 results
  5. Hypertension (High Blood Pressure) : 2 outcomes 6 studies in 27 results
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Drugs Related to Endothelin A Receptor

  1. atrasentan
  2. bosentan (Tracleer)
  3. ZD4054
  4. Epoprostenol (Prostacyclin)
  5. LU 135252
  6. Idiopathic pulmonary hypertension
  7. cyclo(Trp-Asp-Pro-Val-Leu)
  8. Endothelin-1 (Endothelin 1)
  9. Hormones
  10. sitaxsentan
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Therapies Related to Endothelin A Receptor

  1. Castration
  2. Heterologous Transplantation (Xenotransplantation)
  3. Isogeneic Transplantation
  4. Transplants (Transplant)
  5. Cardiopulmonary Bypass (Heart-Lung Bypass)
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