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Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) Summary

Description: The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.

Also Known As: Vascular Endothelial Growth Factor; VEGF; GD-VEGF; Glioma-Derived Vascular Endothelial Cell Growth Factor; VEGF-A Show All >>

Networked: 27623 relevant articles (1327 outcomes, 4790 trials/studies) for this Bio-Agent

Key Diseases for which Vascular Endothelial Growth Factor A is Relevant

  1. Neoplasms (Cancer) : 328 outcomes 1132 studies in 9599 results
  2. Colorectal Neoplasms (Colorectal Cancer) : 71 outcomes 159 studies in 715 results
  3. Anoxia (Hypoxia) : 65 outcomes 382 studies in 4061 results
  4. Macular Degeneration (Age-Related Maculopathy) : 62 outcomes 98 studies in 776 results
  5. Ischemia : 55 outcomes 92 studies in 735 results
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Drugs Related to Vascular Endothelial Growth Factor A

  1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  2. bevacizumab
  3. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
  4. ranibizumab (Lucentis)
  5. Epidermal Growth Factor Receptor (EGF Receptor)
  6. Messenger RNA (mRNA)
  7. Retinaldehyde (Retinal)
  8. Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)
  9. Small Interfering RNA (siRNA)
  10. Protein-Tyrosine Kinases (Tyrosine Kinase)
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Therapies Related to Vascular Endothelial Growth Factor A

  1. Drug Therapy (Chemotherapy)
  2. Injections
  3. Heterologous Transplantation (Xenotransplantation)
  4. Lasers (Laser)
  5. Intravitreal Injections
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