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Integrin beta3 (GPIIIa) Summary

Description: An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.

Also Known As: GPIIIa; CD61 Antigen; Platelet GPIIIa; Platelet Glycoprotein IIIa; beta(3) Integrin Show All >>

Networked: 646 relevant articles (11 outcomes, 71 trials/studies) for this Bio-Agent

Key Diseases for which Integrin beta3 is Relevant

  1. Neoplasms (Cancer) : 8 outcomes 15 studies in 170 results
  2. Melanoma (Melanoma, Malignant) : 1 outcome 8 studies in 59 results
  3. Breast Neoplasms (Breast Cancer) : 1 outcome 4 studies in 27 results
  4. Ovarian Neoplasms (Ovarian Cancer) : 1 outcome 1 study in 9 results
  5. Retinal Degeneration : 1 outcome 1 study in 1 result
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Drugs Related to Integrin beta3

  1. vitaxin
  2. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  3. Transforming Growth Factor beta (TGF-beta)
  4. cyclic arginine-glycine-aspartic acid peptide
  5. CD29 Antigens
  6. Immunoglobulin G (IgG)
  7. Cilengitide
  8. EMD 121974
  9. Fibronectins (Fibronectin)
  10. Proteins (Proteins, Gene)
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Therapies Related to Integrin beta3

  1. Radiotherapy
  2. Heterologous Transplantation (Xenotransplantation)
  3. Microbubbles
  4. Transplants (Transplant)
  5. Ligation
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