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Hyperuricemia Summary

Description: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.

Key Drugs and Agents for Hyperuricemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Uric Acid (Urate) : 47 outcomes 124 studies in 967 results : IBA
  2. Allopurinol (Remid) : 30 outcomes 41 studies in 317 results : FDA 25 Generic
  3. rasburicase (Elitek) : 26 outcomes 13 studies in 77 results : FDA 2
  4. febuxostat : 13 outcomes 25 studies in 83 results : FDA 1
  5. Urate Oxidase (Uricase) : 11 outcomes 13 studies in 100 results : IBA
  6. Xanthine Oxidase : 8 outcomes 14 studies in 96 results : IBA
  7. Losartan (Cozaar) : 4 outcomes 7 studies in 20 results : FDA 24 Generic
  8. Creatinine : 4 outcomes 5 studies in 91 results : IBA
  9. Benzbromarone : 4 outcomes 5 studies in 36 results : IBA
  10. purine : 2 outcomes 12 studies in 103 results : IBA
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Diseases Related to Hyperuricemia

  1. Gout
  2. Hypertension (High Blood Pressure)
  3. Renal Insufficiency (Renal Failure)
  4. Tumor Lysis Syndrome
  5. Hematologic Neoplasms (Hematological Malignancy)
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Key Therapies for Hyperuricemia

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 7 outcomes 5 studies in 64 results
  2. Renal Dialysis (Hemodialysis) : 2 outcomes 2 studies in 20 results
  3. Kidney Transplantation : 2 outcomes 1 study in 25 results
  4. Chinese Traditional Medicine (Traditional Chinese Medicine) : 2 outcomes 1 study in 10 results
  5. Transplants (Transplant) : 1 outcome 12 studies in 51 results
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