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Gestational Trophoblastic Neoplasms (Trophoblastic Neoplasms, Gestational) Summary

Description: A group of interrelated trophoblastic diseases arising from pregnancy. They are commonly associated with hyperplasia of trophoblasts (TROPHOBLAST) and markedly elevated human CHORIONIC GONADOTROPIN. They include HYDATIDIFORM MOLE, invasive mole (HYDATIDIFORM MOLE, INVASIVE), placental-site trophoblastic tumor (TROPHOBLASTIC TUMOR, PLACENTAL SITE), and CHORIOCARCINOMA. These neoplasms have varying propensities for invasion and spread.

Also Known As: Trophoblastic Neoplasms, Gestational; Gestational Trophoblastic Neoplasm; Neoplasm, Gestational Trophoblastic; Neoplasms, Gestational Trophoblastic; Trophoblastic Neoplasm, Gestational

Networked: 50 relevant articles (5 outcomes, 3 trials/studies) for this Disease

Key Drugs and Agents for Gestational Trophoblastic Neoplasms

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Methotrexate (Mexate) : 1 outcome 1 study in 8 results : FDA 8 Generic
  2. Leucovorin (Folinic Acid) : 1 outcome 1 study in 5 results : FDA 6
  3. Chorionic Gonadotropin (Human Chorionic Gonadotropin) : 1 outcome in 8 results : FDA 13 Generic
  4. Fluorouracil (Carac) : 1 outcome in 4 results : FDA 33 Generic
  5. alpha Subunit Glycoprotein Hormones : 1 outcome in 1 result : IBA
  6. Dactinomycin (Ac-De) : 1 study in 4 results : FDA 2 Generic
  7. Leptin : 1 study in 1 result : IBA
  8. Hormones : 1 study in 1 result : IBA
  9. Antigens : 1 study in 1 result : IBA
  10. Gestational trophoblastic disease : 3 results : IBA
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Diseases Related to Gestational Trophoblastic Neoplasms

  1. Neoplasms (Cancer)
  2. Choriocarcinoma
  3. Placental Site Trophoblastic Tumor
  4. Neoplasm Metastasis (Metastasis)
  5. Colorectal Neoplasms (Colorectal Cancer)
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Key Therapies for Gestational Trophoblastic Neoplasms

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 4 outcomes in 24 results
  2. Intravenous Infusions : 1 outcome in 1 result
  3. Lymph Node Excision (Lymph Node Dissection) : 1 result
  4. Immunotherapy : 1 result
  5. Hysterectomy : 1 result
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