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Denys-Drash Syndrome Summary

Description: A disorder of sex development characterized by UROGENITAL ABNORMALITIES; GONADAL DYSGENESIS; and WILMS TUMOR. It is caused by a mutation in the Wilms tumor suppressor gene (GENES, WILMS TUMOR) on chromosome 11.

Also Known As: Wilms Tumor and Pseudohermaphroditism; Denys Drash Syndrome; Syndrome, Denys-Drash; Syndrome, Drash; Drash Syndrome

Networked: 66 relevant articles (2 outcomes, 1 trials/studies) for this Disease

Key Drugs and Agents for Denys-Drash Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclosporine (Ciclosporin) : 1 outcome in 1 result : FDA 20 Generic
  2. diffuse Mesangial sclerosis : 22 results : IBA
  3. DNA (Deoxyribonucleic Acid) : 6 results : IBA
  4. WT1 Proteins : 4 results : IBA
  5. Nonsense Codon (Nonsense Mutation) : 4 results : IBA
  6. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 3 results : IBA
  7. Protein Isoforms (Isoforms) : 3 results : IBA
  8. Transcription Factors (Transcription Factor) : 2 results : IBA
  9. Proteins (Proteins, Gene) : 2 results : IBA
  10. Galloway Mowat syndrome : 2 results : IBA
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Diseases Related to Denys-Drash Syndrome

  1. Wilms Tumor (Wilm's Tumor)
  2. XY Disorders of Sex Development 46 (Male Pseudohermaphroditism)
  3. Disorders of Sex Development (Intersexuality)
  4. Nephrotic Syndrome (Syndrome, Nephrotic)
  5. Renal Insufficiency (Renal Failure)
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Key Therapies for Denys-Drash Syndrome

Efficacy Chart >>
  1. Kidney Transplantation : 1 outcome 1 study in 5 results
  2. Transplants (Transplant) : 1 study in 2 results
  3. Nephrectomy : 6 results
  4. Transplantation (Transplant Recipients) : 5 results
  5. Embolectomy : 1 result
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