Search Login Register

Selective Estrogen Receptor Modulators (SERM) Summary

Description: A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)

Also Known As: SERM; Selective Estrogen Receptor Modulator; SERMs; Estrogen Receptor Modulator, Selective; Estrogen Receptor Modulators, Selective

Networked: 1321 relevant articles (111 outcomes, 209 trials/studies) for this Bio-Agent

Key Diseases for which Selective Estrogen Receptor Modulators is Relevant

  1. Breast Neoplasms (Breast Cancer) : 51 outcomes 93 studies in 579 results
  2. Osteoporosis : 23 outcomes 21 studies in 317 results
  3. Neoplasms (Cancer) : 13 outcomes 21 studies in 161 results
  4. Postmenopausal Osteoporosis : 11 outcomes 7 studies in 135 results
  5. Leiomyoma (Uterine Fibroids) : 4 outcomes 6 studies in 19 results
Show All >>

Drugs Related to Selective Estrogen Receptor Modulators

  1. Selective Estrogen Receptor Modulators (SERM)
  2. Tamoxifen
  3. Raloxifene (Evista)
  4. Estrogens (Estrogen)
  5. Hormones
  6. Aromatase Inhibitors
  7. tartrate salt cis- 1R- (4'- pyrrolidinoethoxyphenyl)- 2S- phenyl- 6- hydroxy- 1,2,3,4- tetrahydronaphthalene (Lasofoxifene)
  8. Toremifene (Fareston)
  9. Diphosphonates
  10. Estradiol (Estrace)
Show All >>

Therapies Related to Selective Estrogen Receptor Modulators

  1. Chemoprevention
  2. Hormone Replacement Therapy (Therapy, Hormone Replacement)
  3. Drug Therapy (Chemotherapy)
  4. Estrogen Replacement Therapy
  5. Heterologous Transplantation (Xenotransplantation)
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.