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Leptin Summary

Description: A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.

Also Known As: Ob Gene Product; Obese Gene Product; Gene Product, Ob; Gene Product, Obese; Ob Protein Show All >>

Networked: 12695 relevant articles (438 outcomes, 2314 trials/studies) for this Bio-Agent

Key Diseases for which Leptin is Relevant

  1. Body Weight (Weight, Body) : 86 outcomes 215 studies in 2748 results
  2. Obesity : 81 outcomes 461 studies in 3743 results
  3. Insulin Resistance : 46 outcomes 204 studies in 1645 results
  4. Weight Loss (Weight Reduction) : 41 outcomes 110 studies in 701 results
  5. Weight Gain : 15 outcomes 69 studies in 557 results
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Drugs Related to Leptin

  1. Insulin (Novolin)
  2. Glucose (Dextrose)
  3. Adiponectin
  4. Resistin
  5. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  6. Triglycerides (Triacylglycerol)
  7. Blood Glucose (Blood Sugar)
  8. Hormones
  9. Leptin Receptors
  10. Adipokines
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Therapies Related to Leptin

  1. Caloric Restriction
  2. Bariatric Surgery
  3. Injections
  4. Gastric Bypass (Roux-en-Y Gastric Bypass)
  5. Gastrectomy
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