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Sleep Paralysis Summary

Description: A common condition characterized by transient partial or total paralysis of skeletal muscles and areflexia that occurs upon awakening from sleep or less often while falling asleep. Stimuli such as touch or sound may terminate the episode, which usually has a duration of seconds to minutes. This condition may occur in normal subjects or be associated with NARCOLEPSY; CATAPLEXY; and hypnagogic HALLUCINATIONS. The pathophysiology of this condition is closely related to the normal hypotonia that occur during REM sleep. (From Adv Neurol 1995;67:245-271)

Also Known As: Paralysis, Sleep

Networked: 40 relevant articles (2 outcomes, 4 trials/studies) for this Disease

Key Drugs and Agents for Sleep Paralysis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Imipramine (Janimine) : 2 outcomes in 3 results : FDA 46 Generic
  2. Clomipramine (Anafranil) : 2 outcomes in 3 results : FDA 9 Generic
  3. Amphetamines : 1 outcome in 1 result : IBA
  4. orexins (orexin) : 2 studies in 6 results : IBA
  5. Antidepressive Agents (Antidepressants) : 1 study in 5 results : IBA
  6. Sodium Oxybate (gamma Hydroxybutyrate) : 1 study in 4 results : FDA 1
  7. Tricyclic Antidepressive Agents (Tricyclic Antidepressants) : 1 study in 2 results : IBA
  8. Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors) : 1 study in 1 result : IBA
  9. Cytokines : 1 study in 1 result : IBA
  10. Sodium : 1 study in 1 result : IBA
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Diseases Related to Sleep Paralysis

  1. Cataplexy
  2. Hallucinations (Hallucination)
  3. Narcolepsy
  4. Parkinsonian Disorders (Parkinsonism)
  5. Sleep Disorders
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Key Therapies for Sleep Paralysis

Efficacy Chart >>
  1. Hypnosis (Mesmerism) : 1 result
  2. Anesthesia : 1 result

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