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Tissue Inhibitor of Metalloproteinase-1 Summary

Description: A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.

Also Known As: Metalloproteinase-1 Tissue Inhibitor; Tissue Inhibitor of Metalloproteinase 1; TIMP-1

Networked: 2251 relevant articles (69 outcomes, 381 trials/studies) for this Bio-Agent

Key Diseases for which Tissue Inhibitor of Metalloproteinase-1 is Relevant

  1. Fibrosis (Cirrhosis) : 14 outcomes 27 studies in 269 results
  2. Neoplasms (Cancer) : 11 outcomes 56 studies in 416 results
  3. Liver Cirrhosis (Hepatic Cirrhosis) : 8 outcomes 16 studies in 109 results
  4. Inflammation : 5 outcomes 12 studies in 116 results
  5. Colorectal Neoplasms (Colorectal Cancer) : 3 outcomes 20 studies in 62 results
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Drugs Related to Tissue Inhibitor of Metalloproteinase-1

  1. Tissue Inhibitor of Metalloproteinase-2
  2. Matrix Metalloproteinases
  3. Messenger RNA (mRNA)
  4. Collagen
  5. Transforming Growth Factor beta1 (TGF beta 1)
  6. Transforming Growth Factor beta (TGF-beta)
  7. Tissue Inhibitor of Metalloproteinases (TIMP)
  8. Matrix Metalloproteinase 2 (Gelatinase A)
  9. Interleukin-6 (Interleukin 6)
  10. Proteins (Proteins, Gene)
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Therapies Related to Tissue Inhibitor of Metalloproteinase-1

  1. Drug Therapy (Chemotherapy)
  2. Combination Drug Therapy (Combination Chemotherapy)
  3. Transplants (Transplant)
  4. Aftercare (After-Treatment)
  5. Transplantation (Transplant Recipients)
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