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Filgrastim (Neupogen) Summary

Description: A hematopoietic growth factor which promotes proliferation and maturation of neutrophil granulocytes. Clinically it is effective in decreasing the incidence of febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive therapy or in reducing the duration of neutropenia and neutropenia-related clinical sequelae in patients with non-myeloid malignancies undergoing myeloblastive chemotherapy followed by BMT. It has also been used in AIDS patients with CMV retinitis being treated with GANCICLOVIR. (Gelman CR, Rumack BH & Hess AJ (eds): DRUGDEX(R) System. MICROMEDEX, Inc., Englewood, Colorado (Edition expires 11/30/95))

Also Known As: Neupogen; r-metHuG-CSF; G CSF Recombinant, Human Methionyl; Recombinant Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF Recombinant, Human Methionyl Show All >>

Networked: 833 relevant articles (94 outcomes, 250 trials/studies) for this Drug

Key Diseases for which Filgrastim is Relevant

  1. Neutropenia : 39 outcomes 76 studies in 324 results
  2. Infection : 9 outcomes 12 studies in 69 results
  3. Breast Neoplasms (Breast Cancer) : 7 outcomes 45 studies in 116 results
  4. Lymphoma (Lymphomas) : 7 outcomes 17 studies in 47 results
  5. Non-Hodgkin Lymphoma (Lymphosarcoma) : 5 outcomes 24 studies in 65 results
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Drugs Related to Filgrastim

  1. Granulocyte Colony-Stimulating Factor (G-CSF)
  2. pegfilgrastim (Neulasta)
  3. Filgrastim (Neupogen)
  4. Doxorubicin (Adriamycin)
  5. Cyclophosphamide (Cytoxan)
  6. Epirubicin (Ellence)
  7. lenograstim
  8. Vincristine (Oncovin)
  9. Anti-Bacterial Agents (Antibiotics)
  10. docetaxel (Taxotere)
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Therapies Related to Filgrastim

  1. Drug Therapy (Chemotherapy)
  2. Transplantation (Transplant Recipients)
  3. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  4. Stem Cell Transplantation
  5. Injections
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