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CD44 Antigens Summary

Description: Acidic sulfated integral membrane glycoproteins expressed in several alternatively spliced and variable glycosylated forms on a wide variety of cell types including mature T-cells, B-cells, medullary thymocytes, granulocytes, macrophages, erythrocytes, and fibroblasts. CD44 antigens are the principle cell surface receptors for hyaluronate and this interaction mediates binding of lymphocytes to high endothelial venules. (From Abbas et al., Cellular and Molecular Immunology, 2d ed, p156)

Also Known As: Antigens, CD44; CD44 Antigen; Hyaluronan Receptor; Hyaluronic Acid Binding Protein; Antigen, CD44 Show All >>

Networked: 196 relevant articles (1 outcomes, 18 trials/studies) for this Bio-Agent

Key Diseases for which CD44 Antigens is Relevant

  1. Inflammation : 1 outcome 1 study in 11 results
  2. Lung Injury : 1 outcome in 1 result
  3. Neoplasms (Cancer) : 2 studies in 66 results
  4. Neoplasm Metastasis (Metastasis) : 2 studies in 21 results
  5. Carcinoma (Carcinomatosis) : 2 studies in 15 results
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Drugs Related to CD44 Antigens

  1. Hyaluronic Acid (Hyaluronan)
  2. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  3. Biotin (Vitamin H)
  4. Aggrecans (Aggrecan)
  5. Vascular Endothelial Growth Factor C
  6. Transcription Factors (Transcription Factor)
  7. Phosphotransferases (Kinase)
  8. Carrier Proteins (Binding Protein)
  9. Avidin
  10. Ovarian epithelial cancer
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Therapies Related to CD44 Antigens

  1. Homologous Transplantation (Allograft)
  2. Nephrectomy
  3. Ligation
  4. Drug Therapy (Chemotherapy)

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