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Seminoma Summary

Description: A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)

Also Known As: Seminomas

Networked: 2091 relevant articles (136 outcomes, 193 trials/studies) for this Disease

Key Drugs and Agents for Seminoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Carboplatin (JM8) : 18 outcomes 27 studies in 110 results : FDA 29 Generic
  2. Cisplatin (Platino) : 18 outcomes 8 studies in 145 results : FDA 6 Generic
  3. Etoposide (VP 16) : 6 outcomes 5 studies in 48 results : FDA 16 Generic
  4. Platinum : 6 outcomes 3 studies in 27 results : IBA
  5. Keratins (Keratin) : 5 outcomes 3 studies in 33 results : IBA
  6. Bleomycin (Blenoxane) : 4 outcomes 1 study in 56 results : FDA 7 Generic
  7. alpha-Fetoproteins (AFP) : 3 outcomes 7 studies in 98 results : IBA
  8. Biological Tumor Markers (Tumor Markers) : 3 outcomes 5 studies in 32 results : IBA
  9. Ifosfamide : 3 outcomes 5 studies in 12 results : FDA 7 Generic
  10. Antibodies : 3 outcomes 3 studies in 37 results : IBA
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Diseases Related to Seminoma

  1. Neoplasms (Cancer)
  2. Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
  3. Neoplasm Metastasis (Metastasis)
  4. Embryonal Carcinoma
  5. Seminoma
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Key Therapies for Seminoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 64 outcomes 31 studies in 500 results
  2. Radiotherapy : 29 outcomes 35 studies in 425 results
  3. Orchiectomy (Orchidectomy) : 17 outcomes 20 studies in 399 results
  4. Lymph Node Excision (Lymph Node Dissection) : 5 outcomes 2 studies in 85 results
  5. Adjuvant Radiotherapy : 4 outcomes 9 studies in 77 results
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