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Germinoma Summary

Description: A malignant neoplasm of the germinal tissue of the GONADS; MEDIASTINUM; or pineal region. Germinomas are uniform in appearance, consisting of large, round cells with vesicular nuclei and clear or finely granular eosinophilic-staining cytoplasm. (Stedman, 265th ed; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1642-3)

Also Known As: Germinomas

Networked: 518 relevant articles (52 outcomes, 39 trials/studies) for this Disease

Key Drugs and Agents for Germinoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cisplatin (Platino) : 4 outcomes 1 study in 28 results : FDA 6 Generic
  2. Etoposide (VP 16) : 3 outcomes 2 studies in 28 results : FDA 16 Generic
  3. alpha-Fetoproteins (AFP) : 3 outcomes 1 study in 32 results : IBA
  4. Chorionic Gonadotropin (Human Chorionic Gonadotropin) : 2 outcomes 5 studies in 48 results : FDA 13 Generic
  5. placental alkaline phosphatase : 2 outcomes 3 studies in 23 results : IBA
  6. Carboplatin (JM8) : 1 outcome 3 studies in 11 results : FDA 29 Generic
  7. Cyclophosphamide (Cytoxan) : 1 outcome 1 study in 7 results : FDA 10 Generic
  8. Transcription Factors (Transcription Factor) : 1 outcome in 8 results : IBA
  9. Ice : 1 outcome in 5 results : IBA
  10. Gadolinium DTPA (Magnevist) : 1 outcome in 3 results : FDA 2
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Diseases Related to Germinoma

  1. Neoplasms (Cancer)
  2. Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
  3. Teratoma (Teratoid Tumor)
  4. Endodermal Sinus Tumor (Endodermal Sinus Tumors)
  5. Embryonal Carcinoma
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Key Therapies for Germinoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 27 outcomes 14 studies in 181 results
  2. Radiotherapy : 20 outcomes 15 studies in 170 results
  3. Combination Drug Therapy (Combination Chemotherapy) : 3 outcomes 2 studies in 8 results
  4. Aftercare (After-Treatment) : 1 outcome 2 studies in 13 results
  5. Adjuvant Chemotherapy : 1 outcome in 7 results
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