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Leukotriene C4 Summary

Description: The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)

Also Known As: Leukotriene C; Leukotriene C-1; Leukotriene C-4; Leukotriene C1; Leukotrienes C Show All >>

Networked: 753 relevant articles (18 outcomes, 72 trials/studies) for this Bio-Agent

Key Diseases for which Leukotriene C4 is Relevant

  1. Asthma (Bronchial Asthma) : 4 outcomes 10 studies in 127 results
  2. Anaphylaxis (Anaphylactic Shock) : 2 outcomes in 18 results
  3. Reperfusion Injury : 2 outcomes in 8 results
  4. Eosinophilia : 1 outcome 2 studies in 12 results
  5. Sneezing : 1 outcome 2 studies in 8 results
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Drugs Related to Leukotriene C4

  1. Leukotriene B4
  2. Leukotriene D4
  3. Histamine (Histamine Dihydrochloride)
  4. Dinoprostone (PGE2)
  5. Leukotrienes
  6. Arachidonate 5-Lipoxygenase (5 Lipoxygenase)
  7. Leukotriene E4
  8. Prostaglandin D2
  9. Lipoxygenase (Lipoxygenase-1)
  10. Platelet Activating Factor
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Therapies Related to Leukotriene C4

  1. Ligation
  2. Intra-Arterial Infusions
  3. Artificial Eye (Artificial Eyes)
  4. Injections
  5. Intravenous Injections
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