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Epilepsia Partialis Continua Summary

Description: A variant of epilepsy characterized by continuous focal jerking of a body part over a period of hours, days, or even years without spreading to other body regions. Contractions may be aggravated by movement and are reduced, but not abolished during sleep. ELECTROENCEPHALOGRAPHY demonstrates epileptiform (spike and wave) discharges over the hemisphere opposite to the affected limb in most instances. The repetitive movements may originate from the CEREBRAL CORTEX or from subcortical structures (e.g., BRAIN STEM; BASAL GANGLIA). This condition is associated with Russian Spring and Summer encephalitis (see ENCEPHALITIS, TICK BORNE); Rasmussen syndrome (see ENCEPHALITIS); MULTIPLE SCLEROSIS; DIABETES MELLITUS; BRAIN NEOPLASMS; and CEREBROVASCULAR DISORDERS. (From Brain, 1996 April;119(pt2):393-407; Epilepsia 1993;34;Suppl 1:S29-S36; and Adams et al., Principles of Neurology, 6th ed, p319)

Also Known As: Chronic Progressive Epilepsia Partialis Continua; Epilepsia Partialis Continua, Chronic Progressive; Kojevnikov's Epilepsy; Kojewnikov's Epilepsy; Kojewnikow's Syndrome Show All >>

Networked: 146 relevant articles (4 outcomes, 8 trials/studies) for this Disease

Key Drugs and Agents for Epilepsia Partialis Continua

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. erucylphosphocholine : 1 outcome 8 studies in 100 results : IBA
  2. Piracetam (Nootropil) : 1 outcome in 1 result : IBA
  3. Flucytosine (Ancobon) : 1 outcome in 1 result : FDA 1
  4. Amphotericin B (Amphotericin) : 1 outcome in 1 result : FDA 12 Generic
  5. lacosamide : 1 outcome in 1 result : FDA 3
  6. Lennox-Gastaut type Epileptic encephalopathy : 1 study in 4 results : IBA
  7. Antibodies : 6 results : IBA
  8. Glutamate Receptors (Glutamate Receptor) : 5 results : IBA
  9. N-Methylaspartate (NMDA) : 3 results : IBA
  10. Valproic Acid (Valproate, Semisodium) : 3 results : FDA 51 Generic
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Diseases Related to Epilepsia Partialis Continua

  1. Seizures (Seizure)
  2. Status Epilepticus (Complex Partial Status Epilepticus)
  3. Myoclonus (Nocturnal Myoclonus)
  4. Epilepsy (Aura)
  5. Meningitis
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Key Therapies for Epilepsia Partialis Continua

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 3 results
  2. Vagus Nerve Stimulation : 2 results
  3. Ketogenic Diet : 1 result
  4. Stem Cell Transplantation : 1 result
  5. Transplants (Transplant) : 1 result
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