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Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) Summary

Description: The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

Also Known As: Antiphospholipid Antibody Syndrome; Syndrome, Antiphospholipid; Syndrome, Antiphospholipid Antibody; Anti-Phospholipid Antibody Syndrome; Anti-Phospholipid Syndrome Show All >>

Networked: 3487 relevant articles (57 outcomes, 235 trials/studies) for this Disease

Key Drugs and Agents for Antiphospholipid Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Aspirin (Acetylsalicylic Acid) : 11 outcomes 17 studies in 130 results : FDA 80 Generic
  2. Heparin (Liquaemin) : 8 outcomes 14 studies in 152 results : FDA 74 Generic
  3. Warfarin (Coumadin) : 5 outcomes 9 studies in 77 results : FDA 21 Generic
  4. Intravenous Immunoglobulins (IVIG) : 5 outcomes 4 studies in 29 results : FDA 1
  5. rituximab (Mabthera) : 5 outcomes 3 studies in 41 results : FDA 3
  6. Antiphospholipid Antibodies : 3 outcomes 47 studies in 933 results : IBA
  7. Anticardiolipin Antibodies : 3 outcomes 24 studies in 356 results : IBA
  8. Lupus Coagulation Inhibitor (Lupus Anticoagulant) : 3 outcomes 13 studies in 316 results : IBA
  9. Anticoagulants : 3 outcomes 2 studies in 86 results : IBA
  10. eculizumab : 3 outcomes in 9 results : FDA 2
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Diseases Related to Antiphospholipid Syndrome

  1. Systemic Lupus Erythematosus (Libman-Sacks Disease)
  2. Thrombosis (Thrombus)
  3. Stroke (Strokes)
  4. Thrombocytopenia (Thrombopenia)
  5. Venous Thrombosis (Deep-Vein Thrombosis)
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Key Therapies for Antiphospholipid Syndrome

Efficacy Chart >>
  1. Plasmapheresis : 3 outcomes in 17 results
  2. Plasma Exchange : 2 outcomes in 27 results
  3. Transplantation (Transplant Recipients) : 1 outcome 1 study in 7 results
  4. Hormone Replacement Therapy (Therapy, Hormone Replacement) : 1 outcome 1 study in 3 results
  5. Drug Therapy (Chemotherapy) : 1 outcome in 6 results
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