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NF-kappa B (NF-kB) Summary

Description: Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.

Also Known As: NF-kB; NF-kappaB; Nuclear Factor kappa B; Ig-EBP-1; Enhancer-Binding Protein, Immunoglobulin Show All >>

Networked: 11194 relevant articles (378 outcomes, 1336 trials/studies) for this Bio-Agent

Key Diseases for which NF-kappa B is Relevant

  1. Neoplasms (Cancer) : 47 outcomes 184 studies in 2110 results
  2. Inflammation : 41 outcomes 169 studies in 2190 results
  3. Colitis : 19 outcomes 16 studies in 138 results
  4. Sepsis (Septicemia) : 12 outcomes 20 studies in 145 results
  5. Reperfusion Injury : 12 outcomes 12 studies in 145 results
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Drugs Related to NF-kappa B

  1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  2. Cytokines
  3. Transcription Factors (Transcription Factor)
  4. Transcription Factor AP-1 (Transcription Factor AP 1)
  5. NF-kappa B (NF-kB)
  6. Curcumin
  7. DNA (Deoxyribonucleic Acid)
  8. Small Interfering RNA (siRNA)
  9. Proteasome Endopeptidase Complex (Proteasome)
  10. Messenger RNA (mRNA)
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Therapies Related to NF-kappa B

  1. Drug Therapy (Chemotherapy)
  2. Transplants (Transplant)
  3. Resuscitation
  4. Oral Administration
  5. Transplantation (Transplant Recipients)
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