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Granulocyte Colony-Stimulating Factor (G-CSF) Summary

Description: A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

Also Known As: G-CSF; Colony-stimulating factor, granulocyte

Networked: 7243 relevant articles (752 outcomes, 1342 trials/studies) for this Bio-Agent

Key Diseases for which Granulocyte Colony-Stimulating Factor is Relevant

  1. Neutropenia : 146 outcomes 147 studies in 1468 results
  2. Infection : 95 outcomes 89 studies in 741 results
  3. Neoplasms (Cancer) : 45 outcomes 165 studies in 892 results
  4. Acute Myeloid Leukemia (Acute Myelogenous Leukemia) : 44 outcomes 55 studies in 365 results
  5. Myocardial Infarction : 35 outcomes 67 studies in 189 results
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Drugs Related to Granulocyte Colony-Stimulating Factor

  1. Granulocyte Colony-Stimulating Factor (G-CSF)
  2. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
  3. Cytarabine (Cytosar-U)
  4. Filgrastim (Neupogen)
  5. Anti-Bacterial Agents (Antibiotics)
  6. Cyclophosphamide (Cytoxan)
  7. JM 3100
  8. Etoposide (VP 16)
  9. Erythropoietin
  10. Doxorubicin (Adriamycin)
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Therapies Related to Granulocyte Colony-Stimulating Factor

  1. Drug Therapy (Chemotherapy)
  2. Transplantation (Transplant Recipients)
  3. Hematopoietic Stem Cell Mobilization
  4. Transplants (Transplant)
  5. Bone Marrow Transplantation (Transplantation, Bone Marrow)
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