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Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Summary

Description: An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

Also Known As: GM-CSF; CSF-2; Colony Stimulating Factor, Granulocyte Macrophage; TC-GM-CSF; Tumor-Cell Human GM Colony-Stimulating Factor; Cell-Stimulating Factor, Histamine-Producing; Granulocyte Macrophage Colony Stimulating Factor; Histamine Producing Cell Stimulating Factor; Tumor Cell Human GM Colony Stimulating Factor; CSF-GM; Colony-Stimulating Factor, Granulocyte-Macrophage; Histamine-Producing Cell-Stimulating Factor; Colony-stimulating factor 2

Networked: 6186 relevant articles (478 outcomes, 1092 trials/studies) for this Bio-Agent

Key Diseases for which Granulocyte-Macrophage Colony-Stimulating Factor is Relevant

  1. Neoplasms (Cancer) : 147 outcomes 251 studies in 1474 results
  2. Infection : 47 outcomes 59 studies in 559 results
  3. Neutropenia : 40 outcomes 57 studies in 342 results
  4. Melanoma (Melanoma, Malignant) : 16 outcomes 76 studies in 272 results
  5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia) : 13 outcomes 44 studies in 242 results
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Drugs Related to Granulocyte-Macrophage Colony-Stimulating Factor

  1. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
  2. Granulocyte Colony-Stimulating Factor (G-CSF)
  3. Interleukin-2 (IL2)
  4. Cytokines
  5. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  6. Vaccines
  7. Interleukin-12 (IL 12)
  8. Interleukin-3 (Interleukin 3)
  9. Antigens
  10. Cytarabine (Cytosar-U)
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Therapies Related to Granulocyte-Macrophage Colony-Stimulating Factor

  1. Drug Therapy (Chemotherapy)
  2. Immunotherapy
  3. Radiotherapy
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  5. Aftercare (After-Treatment)
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