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Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa) Summary

Description: Form of epidermolysis bullosa characterized by atrophy of blistered areas, severe scarring, and nail changes. It is most often present at birth or in early infancy and occurs in both autosomal dominant and recessive forms. All forms of dystrophic epidermolysis bullosa result from mutations in COLLAGEN TYPE VII, a major component fibrils of BASEMENT MEMBRANE and EPIDERMIS.

Also Known As: Dystrophic Epidermolysis Bullosa; Epidermolysis Bullosa Dystrophica, Dominant; Cockayne-Touraine Type Epidermolysis Bullosa; Epidermolysis Bullosa Dystrophica, Cockayne-Touraine Type; Epidermolysis Bullosa Dystrophica, Hallopeau-Siemens Type Show All >>

Networked: 507 relevant articles (15 outcomes, 32 trials/studies) for this Disease

Key Drugs and Agents for Epidermolysis Bullosa Dystrophica

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Phenytoin (Dilantin) : 3 outcomes 2 studies in 13 results : FDA 9 Generic
  2. Collagen Type VII : 2 outcomes 7 studies in 202 results : IBA
  3. TNFR-Fc fusion protein (etanercept) : 2 outcomes in 2 results : FDA 2
  4. Vitamin E : 1 outcome 1 study in 2 results : FDA 13 Generic
  5. Prednisone (Sone) : 1 outcome 1 study in 1 result : FDA 119 Generic
  6. Tacrolimus (Prograf) : 1 outcome in 2 results : FDA 7 Generic
  7. Genetic Markers (Genetic Marker) : 1 outcome in 2 results : IBA
  8. Serine Proteases (Serine Protease) : 1 outcome in 1 result : IBA
  9. Losartan (Cozaar) : 1 outcome in 1 result : FDA 24 Generic
  10. Timolol (Blocadren) : 1 outcome in 1 result : FDA 56 Generic
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Diseases Related to Epidermolysis Bullosa Dystrophica

  1. Pathologic Constriction (Stenosis)
  2. Psoriasis (Pustulosis Palmaris et Plantaris)
  3. Congenital Abnormalities (Deformity)
  4. Psoriatic Arthritis
  5. Hemangioma (Angioma)
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Key Therapies for Epidermolysis Bullosa Dystrophica

Efficacy Chart >>
  1. Transplantation (Transplant Recipients) : 1 outcome in 8 results
  2. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 1 outcome in 2 results
  3. Autologous Transplantation : 1 outcome in 2 results
  4. Phototherapy (Light Therapy) : 1 outcome in 2 results
  5. Prostheses and Implants (Prosthesis) : 3 studies in 3 results
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