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Cadherins (E-Cadherin) Summary

Description: Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.

Also Known As: E-Cadherin; Cadherin-1; Cadherin-2; Cadherin-3; Epithelial-Cadherins Show All >>

Networked: 6849 relevant articles (102 outcomes, 1095 trials/studies) for this Bio-Agent

Key Diseases for which Cadherins is Relevant

  1. Neoplasms (Cancer) : 36 outcomes 282 studies in 3085 results
  2. Neoplasm Metastasis (Metastasis) : 10 outcomes 134 studies in 1262 results
  3. Carcinoma (Carcinomatosis) : 7 outcomes 170 studies in 1200 results
  4. Breast Neoplasms (Breast Cancer) : 6 outcomes 83 studies in 574 results
  5. Adenocarcinoma : 3 outcomes 56 studies in 310 results
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Drugs Related to Cadherins

  1. Cadherins (E-Cadherin)
  2. beta Catenin
  3. Messenger RNA (mRNA)
  4. Vimentin
  5. Biological Markers (Surrogate Marker)
  6. Estrogens (Estrogen)
  7. Fibronectins (Fibronectin)
  8. Antigens
  9. Syndecan-1 (Syndecan 1)
  10. Collagenases (Collagenase)
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Therapies Related to Cadherins

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Transplantation (Transplant Recipients)
  4. Gastrectomy
  5. Radioimmunotherapy
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