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Pentostatin (Nipent) Summary

Description: A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.

Also Known As: Nipent; CI-825; Co-Vidarabine; Deoxycoformycin; Lederle Brand of Pentostatin Show All >>

Networked: 403 relevant articles (52 outcomes, 74 trials/studies) for this Drug

Key Diseases for which Pentostatin is Relevant

  1. Hairy Cell Leukemia : 28 outcomes 17 studies in 111 results
  2. Leukemia : 4 outcomes 7 studies in 39 results
  3. Lymphoma (Lymphomas) : 4 outcomes 4 studies in 23 results
  4. Neoplasms (Cancer) : 3 outcomes 8 studies in 25 results
  5. Splenomegaly : 3 outcomes in 4 results
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Drugs Related to Pentostatin

  1. Cladribine
  2. Pentostatin (Nipent)
  3. Adenosine Deaminase
  4. Interferon-alpha (Interferon Alfa)
  5. purine
  6. rituximab (Mabthera)
  7. Cyclophosphamide (Cytoxan)
  8. Interferons
  9. fludarabine
  10. Deoxyadenosines (Deoxyadenosine)
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Therapies Related to Pentostatin

  1. Splenectomy
  2. Transplants (Transplant)
  3. Aftercare (After-Treatment)
  4. Drug Therapy (Chemotherapy)
  5. Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
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